Featured Research

from universities, journals, and other organizations

Low Birth Weight Linked To Heart Disease And Diabetes Risk In Adulthood

Date:
April 3, 2009
Source:
The Endocrine Society
Summary:
Lower weight at birth may increase inflammatory processes in adulthood, which are associated with chronic diseases such as heart disease and diabetes, according to a new study.

Lower weight at birth may increase inflammatory processes in adulthood, which are associated with chronic diseases such as heart disease and diabetes, according to a new study.

Both the fetal and infancy periods are sensitive, critical stages of growth and development. Studies have previously suggested babies with lower weight at birth are at a higher risk for developing chronic diseases but until now, there has been little understanding to explain why. This study suggests an association between lower weight at birth and inflammation in adulthood may provide that explanation.

Inflammation is a normal physiologic response of the body, and serves as a host defense which provides protective response to infection or tissue injury. If the source of infection or injury is not repressed, low-grade inflammation can persist and may promote the development of heart disease or diabetes.

Earlier studies have found that babies born small for gestational age have weak immune systems, but at six years old have more white blood cells than babies born at a normal weight. White blood cells are cells of the immune system that defend the body against both infectious disease and foreign materials. These findings suggest that age might amplify the association between early growth and inflammatory processes.

In this study, researchers followed 5,619 children born in 1966 and followed them up until they reached adulthood. As compared to children with 'normal' weight in the first year of life, researchers observed that babies born relatively smaller and gained the least weight during infancy had a higher number of white blood cells, an indicator of inflammation, in adulthood.

"Our findings suggest that the link between poorer growth early in life and these adult chronic diseases may involve inflammation as a common underlying factor," said Dr. Dexter Canoy, MD, PhD, of the University of Manchester in the UK and lead researcher of the study. "Ensuring appropriate growth during this narrow 'window' in early development may confer lifelong benefits to health."

Other researchers working on the study include Anneli Pouta, Aimo Ruokonen, Anna-Liisa Hartikainen, Pekka Saikku and Marjo-Riitta Jδrvelin of the University of Oulu in Finland and Imperial College London in the UK.


Story Source:

The above story is based on materials provided by The Endocrine Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Weight at birth and infancy in relation to adult leukocyte count: a population-based study of 5,619 men and women followed from the fetal period to adulthood. Journal of Clinical Endocrinology & Metabolism, June 2009

Cite This Page:

The Endocrine Society. "Low Birth Weight Linked To Heart Disease And Diabetes Risk In Adulthood." ScienceDaily. ScienceDaily, 3 April 2009. <www.sciencedaily.com/releases/2009/04/090401101846.htm>.
The Endocrine Society. (2009, April 3). Low Birth Weight Linked To Heart Disease And Diabetes Risk In Adulthood. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2009/04/090401101846.htm
The Endocrine Society. "Low Birth Weight Linked To Heart Disease And Diabetes Risk In Adulthood." ScienceDaily. www.sciencedaily.com/releases/2009/04/090401101846.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) — A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
Too Few Teens Receiving HPV Vaccination, CDC Says

Too Few Teens Receiving HPV Vaccination, CDC Says

Newsy (July 24, 2014) — The Centers for Disease Control and Prevention is blaming doctors for the low number of children being vaccinated for HPV. Video provided by Newsy
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) — The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) — Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:  

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile iPhone Android Web
          Follow Facebook Twitter Google+
          Subscribe RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins