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Anti-aging Cosmetic Reduced Wrinkles In Clinical Trial

Date:
May 3, 2009
Source:
University of Manchester
Summary:
Scientists testing a cosmetic anti-aging product sold commercially have shown it can clinically reduce wrinkles and improve the appearance of skin damaged by everyday exposure to sunlight.

Scientists testing a cosmetic anti-ageing product sold commercially have shown it can clinically reduce wrinkles and improve the appearance of skin damaged by everyday exposure to sunlight.

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Dermatologists at The University of Manchester carried out a clinical trial on 60 volunteers with typical signs of sun-damaged skin and found that the cosmetic, No7 Protect & Perfect Intense Beauty Serum, could improve some of these clinical features.

The study showed that 70% of individuals using the beauty product had significantly fewer wrinkles after 12 months of daily use compared to volunteers using a placebo.

The research team, headed by Professor of Dermatology Chris Griffiths, reported last year that the original No7 Protect & Perfect Beauty Serum stimulated the production of fibrillin-1, a protein that promotes elasticity in the skin.

For this latest, year-long study, the researchers first wanted to discover whether the new No7 Protect & Perfect Intense Beauty Serum also promoted fibrillin-1 production but also wished to test whether this would result in a reduction in wrinkles, as has been demonstrated with prescription retinoids.

“Very few over-the-counter cosmetic ‘anti-ageing’ products have been subjected to a rigorous, scientific trial to prove their effectiveness,” said Professor Griffiths, who is based in the University’s School of Translational Medicine at Salford Royal Foundation Hospital.

“Although prescription retinoids can have a reparative effect on photo-aged skin, there is scant evidence that any of the plethora of cosmetic ‘anti-ageing’ products can produce similar effects.”

The clinical trial – funded by Boots, the makers of the No7 product range – was carried out using standard scientific protocols. Having established that the No7 Protect & Perfect Intense Beauty Serum did increase fibrillin-1 production, 60 volunteers – 11 men and 49 women aged 45 to 80 years – were recruited to test its efficacy.

The No7 Protect & Perfect Intense Beauty Serum and a control formulation containing no anti-ageing ingredients were supplied in identical, coded packages, so neither investigators nor volunteers were aware as to the treatment of each individual. Thirty volunteers were assigned the No7 Protect & Perfect Intense Beauty Serum and 30 used the placebo formulation.

“Our findings demonstrate that a commercially-available cosmetic can produce significant improvement in the appearance of facial wrinkles following long-term use,” said Professor Griffiths.

“It is rare for such benefits to be reported for an over-the-counter anti-ageing product and this study paves the way for larger studies with more statistical power.”


Story Source:

The above story is based on materials provided by University of Manchester. Note: Materials may be edited for content and length.


Journal Reference:

  1. R.E.B. Watson, S. Ogden, L.F. Cotterell, J.J. Bowden, J.Y. Bastrilles, S.P. Long, C.E.M. Griffiths. A cosmetic 'anti-ageing' product improves photoaged skin: a double-blind, randomized controlled trial (p ). British Journal of Dermatology, April 28, 2009 DOI: 10.1111/j.1365-2133.2009.09216.x

Cite This Page:

University of Manchester. "Anti-aging Cosmetic Reduced Wrinkles In Clinical Trial." ScienceDaily. ScienceDaily, 3 May 2009. <www.sciencedaily.com/releases/2009/04/090428093044.htm>.
University of Manchester. (2009, May 3). Anti-aging Cosmetic Reduced Wrinkles In Clinical Trial. ScienceDaily. Retrieved March 6, 2015 from www.sciencedaily.com/releases/2009/04/090428093044.htm
University of Manchester. "Anti-aging Cosmetic Reduced Wrinkles In Clinical Trial." ScienceDaily. www.sciencedaily.com/releases/2009/04/090428093044.htm (accessed March 6, 2015).

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