Featured Research

from universities, journals, and other organizations

Even Mildly Premature Infants Have Increased Risk Of Common Respiratory Tract Infection

Date:
May 12, 2009
Source:
Kaiser Permanente
Summary:
Even mildly premature infants (gestational age 33 weeks - 36 weeks) have an increased risk of medically attended respiratory syncytial virus infection, the leading cause of lower respiratory tract infection in infants and young children and can lead to pneumonia, according to a new study. The RSV infection risk is higher among infants exposed to supplemental oxygen or assisted ventilation during the neonatal period.

Even mildly premature infants (gestational ages of 33 weeks through 36 weeks) have an increased risk of medically attended respiratory syncytial virus infection, which is the leading cause of lower respiratory tract infection in infants and young children and can lead to pneumonia in babies, according to a Kaiser Permanente Division of Research study.

Related Articles


The RSV infection risk is higher among infants exposed to supplemental oxygen or assisted ventilation during the neonatal period, said the researchers, explaining that the need for oxygen is sometimes unavoidable for babies who need intensive care.

The results of the study are being presented at the Pediatric Academic Societies Annual Meeting to be held in Baltimore on Tuesday, May 5.

"Although extreme prematurity is a known risk factor for severe RSV infection, this study helped us to learn more about risk factors for RSV infection among mildly premature infants. We detected an increased risk even in babies born at 37 weeks," said the study's lead investigator Gabriel J. Escobar, MD, a hospital-based pediatrician and research scientist with the Kaiser Permanente Division of Research in Oakland, Calif. "Further research is needed to determine whether strategies to prevent or mitigate RSV infections are indicated in late preterm infants."

The study included 108,794 babies at least 33 weeks gestation discharged from six Kaiser Permanente hospitals between January 1996 and December 2002. Compared to babies 38-40 weeks, babies born at 37 weeks had a 37 percent increased odds of RSV infection, while babies born at 34-36 weeks had a 70 percent increased odds. In contrast, babies born at 41 or more weeks had 14 percent decreased odds. Even after controlling for prematurity, babies who received supplemental oxygen during the birth hospitalization had a 50 to 120 percent increased odds of medically attended RSV infection in the first year of life.

Researchers used a retrospective cohort study design using logistic regression and Cox proportional hazards modeling to control for varying follow-up lengths.

Additional researchers on the study include: Patricia Kipnis, Ph.D., Arona Ragins, MA, Sherian Xu Li, MS, and Laura Prager, MD, Pharm D, all with Kaiser Permanente; and Jennifer Graff with Medimmune.

Funding was provided by Medimmune, LLC.


Story Source:

The above story is based on materials provided by Kaiser Permanente. Note: Materials may be edited for content and length.


Cite This Page:

Kaiser Permanente. "Even Mildly Premature Infants Have Increased Risk Of Common Respiratory Tract Infection." ScienceDaily. ScienceDaily, 12 May 2009. <www.sciencedaily.com/releases/2009/05/090505111647.htm>.
Kaiser Permanente. (2009, May 12). Even Mildly Premature Infants Have Increased Risk Of Common Respiratory Tract Infection. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2009/05/090505111647.htm
Kaiser Permanente. "Even Mildly Premature Infants Have Increased Risk Of Common Respiratory Tract Infection." ScienceDaily. www.sciencedaily.com/releases/2009/05/090505111647.htm (accessed October 31, 2014).

Share This



More Health & Medicine News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins