Featured Research

from universities, journals, and other organizations

Ways To Predict Exercise-induced Asthma And Its Severity Without Requiring An Exercise Challenge

Date:
June 4, 2009
Source:
Indiana University
Summary:
Two new studies have explored the potential use of two simple tests for not only predicting whether someone has exercise-induced asthma (EIA) but also its severity, without subjecting the patient to an exercise challenge.

Two Indiana University studies have explored the potential use of two simple tests for not only predicting whether someone has exercise-induced asthma (EIA) but also its severity, without subjecting the patient to an exercise challenge.

Related Articles


One test involves measuring exhaled breath levels of nitric oxide. The other involved measuring the pH level of exhaled breath. Researchers found that both tests could be effective at predicting EIA and its severity. Both tests can be performed in a doctor's office while the patient is at rest.

With EIA, vigorous exercise triggers an acute narrowing of the airway afterward, making breathing difficult. Around 80 percent of people with asthma have this condition, also called exercise-induced bronchoconstriction. EIA also is found in an estimated 10 percent or more of elite athletes and as much as 10 percent of the general population without asthma.

Previous research has shown that pre-exercise fraction of exhaled nitric oxide (FENO) levels, which is a marker of airway inflammation, is elevated in people who have EIA. FENO levels also are associated with post-exercise closure of large airways. This study demonstrated the same positive relationship between FENO and closure of small airways after exercise. The study involved 12 people with EIA and six people without EIA. Their FENO levels were measured before the study participants underwent a eucapnic voluntary hyperventilation challenge for six minutes. "Our study found that exhaled nitric oxide may be a useful tool in predicting EIB and the magnitude of both large and small airway changes as a result of exercise," said lead author Louise Turner, a doctoral student in the Department of Kinesiology. "It involves the use of a simple piece of equipment and does not require exercise." Co-authors of the study include Sandra Tecklenburg-Lund, Joel M. Stager and Mickleborough, all of IU's Department of Kinesiology in the School of Health, Physical Education and Recreation. The study, "Exhaled Nitric Oxide Is Correlated With Changes in Small And Large Airway Obstruction," was presented during the Respiratory Session on May 29.

The second study found that study participants with EIA had significantly lower levels of exhaled pH, which might "indicate acidification of the airways in individuals with airway hyperresponsiveness," according to the study. The pH level also was related to the degree of closure of the small airways. This study involved 23 participants who had asthma and EIA and eight people who did not. The study participants were asked to breathe normally for 10 minutes while their exhaled breath was collected. They then underwent a eucapnic voluntary hyperventilation challenge for six minutes. Their pulmonary function was measured several times before and after the hyperventilation. Coauthors include lead author Tecklenburg-Lund, Turner, Stager and Mickleborough. The study, "Exhaled Breath Condensate pH is Correlated With Post-exercise Small Airway Obstruction," was presented during the Respiratory Session on May 29.


Story Source:

The above story is based on materials provided by Indiana University. Note: Materials may be edited for content and length.


Cite This Page:

Indiana University. "Ways To Predict Exercise-induced Asthma And Its Severity Without Requiring An Exercise Challenge." ScienceDaily. ScienceDaily, 4 June 2009. <www.sciencedaily.com/releases/2009/05/090530172218.htm>.
Indiana University. (2009, June 4). Ways To Predict Exercise-induced Asthma And Its Severity Without Requiring An Exercise Challenge. ScienceDaily. Retrieved April 21, 2015 from www.sciencedaily.com/releases/2009/05/090530172218.htm
Indiana University. "Ways To Predict Exercise-induced Asthma And Its Severity Without Requiring An Exercise Challenge." ScienceDaily. www.sciencedaily.com/releases/2009/05/090530172218.htm (accessed April 21, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, April 21, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Humanoid Robot Can Recognise and Interact With People

Humanoid Robot Can Recognise and Interact With People

Reuters - Innovations Video Online (Apr. 20, 2015) An ultra-realistic humanoid robot called &apos;Han&apos; recognises and interprets people&apos;s facial expressions and can even hold simple conversations. Developers Hanson Robotics hope androids like Han could have uses in hospitality and health care industries where face-to-face communication is vital. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Labour Party Warns Britain's Health Service 'on Life Support'

Labour Party Warns Britain's Health Service 'on Life Support'

AFP (Apr. 20, 2015) Britain&apos;s opposition Labour Party Monday claimed the National Health Service (NHS) was &apos;on life support&apos; as it turned its attention to the state-run service, which is a key issue for the UK&apos;s May 7 general election. Video provided by AFP
Powered by NewsLook.com
Sierra Leone Students Back to School After Long Ebola Closure

Sierra Leone Students Back to School After Long Ebola Closure

Reuters - News Video Online (Apr. 20, 2015) After an eight-month break, children in Sierra Leone return to school for the first time since the beginning of the Ebola outbreak. Nathan Frandino reports. Video provided by Reuters
Powered by NewsLook.com
Teen E-Cigarette Use Triples, Government Debates Regulations

Teen E-Cigarette Use Triples, Government Debates Regulations

Newsy (Apr. 19, 2015) The Centers for Disease Control and Prevention says in 2014, 13.4 percent of high school students reported smoking an e-cigarette within 30 days. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins