Featured Research

from universities, journals, and other organizations

Diagnosis Of Arthritis Five Years Earlier In Childless Women Compared To Those With Children

Date:
June 11, 2009
Source:
European League Against Rheumatism
Summary:
Nulliparous women (those who have not given birth to children) are diagnosed with chronic arthritides (including ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis an average of 5.2 years before parous women (those who have given birth to children), according to a new study.

Nulliparous women (those who have not given birth to children) are diagnosed with chronic arthritides (including ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis (RA) an average of 5.2 years before parous women (those who have given birth to children), according to a new study presented June 11 at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark.

Previous studies have highlighted that pregnancy may be a protective factor against the development of RA, whereas this is the first study to assess the effect of pregnancy and having children on the development of chronic arthritic conditions in premenopausal women. Within the study, the mean age at time of diagnosis for nulliparous women was 26 years, compared with 31.2 years for parous women (p< 0.001).

Rheumatoid factor (an autoantibody sometimes found in the immune systems of people with RA) was also present in 37.1% of the nulliparous women compared with 41.1% of the parous women (p=0.21), which, although not statistically significant, may indicate that the parous women studied may possess a higher disposition to developing arthritis than the nulliparous women.

Dr Marianne Wallenius, of the Norwegian University of Science and Technology, Norway, who led the study, said: "Arthritic conditions tend to occur more commonly in women, particularly those of childbearing age. Some symptoms of RA, for example, can improve during pregnancy, but our study indicates that the processes of pregnancy and childbearing could delay the onset of arthritic conditions. Continued examination of the complex interactions between the female reproductive processes and the epidemiology of RA could yield further interesting insights."

The retrospective study analysed 557 women aged 18-45 years from the Norwegian Disease Modifying Antirheumatic Drug (NOR-DMARD) study, who were all diagnosed with chronic arthritides before the age of 45 years. Information about parous status was confirmed through linking the NOR-DMARD patient cohort with the Medical Birth Registry of Norway (MBRN).

The time of diagnosis was recorded at the time of enrollment into the study and group comparisons were performed with Mann-Whitney U test for continuous variables and chi-square tests for categorical variables. Cox multiple regression analyses were used to compare the age at diagnosis for nulliparous and parous women. The analyses were adjusted for smoking, length of education and age at the time of the current analyses.

Of the 557 women identified, 163 were nulliparous and 394 were parous (with a minimum of one delivery). The mean age at the time of the current analyses was 36.2 years for the nulliparious women, and 41.1 years for the parous women (p< 0.001).

Nulliparous women were found to have a significantly higher educational level than parous women (p=0.02), although smoking habits were not found to be significantly different between the groups (p=0.11). Unadjusted in the Cox multiple regression analyses, the nulliparous women were diagnosed at a significantly earlier age than the parous women: RR (95% CI) 1.83 (p< 0.001). However, when adjusted for educational level, smoking and age at the current analyses, a significant difference was still observed: RR (95% CI) 1.23 (p=0.04).


Story Source:

The above story is based on materials provided by European League Against Rheumatism. Note: Materials may be edited for content and length.


Cite This Page:

European League Against Rheumatism. "Diagnosis Of Arthritis Five Years Earlier In Childless Women Compared To Those With Children." ScienceDaily. ScienceDaily, 11 June 2009. <www.sciencedaily.com/releases/2009/06/090611110948.htm>.
European League Against Rheumatism. (2009, June 11). Diagnosis Of Arthritis Five Years Earlier In Childless Women Compared To Those With Children. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2009/06/090611110948.htm
European League Against Rheumatism. "Diagnosis Of Arthritis Five Years Earlier In Childless Women Compared To Those With Children." ScienceDaily. www.sciencedaily.com/releases/2009/06/090611110948.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Peace Corps Pulls Workers From W. Africa Over Ebola Fears

Peace Corps Pulls Workers From W. Africa Over Ebola Fears

Newsy (July 30, 2014) The Peace Corps is one of several U.S.-based organizations to pull workers out of West Africa because of the Ebola outbreak. Video provided by Newsy
Powered by NewsLook.com
Weather Kills 2K A Year, But Storms Aren't The Main Offender

Weather Kills 2K A Year, But Storms Aren't The Main Offender

Newsy (July 30, 2014) Health officials say 2,000 deaths occur each year in the U.S. due to weather, but it's excessive heat and cold that claim the most lives. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins