Featured Research

from universities, journals, and other organizations

Advances In Liver Surgery Enable The Prospect Of Curative Treatment For More Patients

Date:
June 15, 2009
Source:
World Journal of Gastroenterology
Summary:
Patients with liver metastases from colorectal cancer are increasingly benefiting from curative surgical treatment. A research group in Barcelona investigated the time effects on their patients operated on for colorectal liver metastases and observed no changes in patient survival and cancer recurrence with improvements in hospital stay, despite including patients with unfavorable prognostic factors, possibly because of the recent improvements in preoperative imaging, surgical technique and complementary cancer treatments.

Although many prognostic factors predicting survival and cancer recurrence in patients undergoing surgery for colorectal liver metastases are already identified, the effects of newly introduced technologies and new drugs in the treatment of these patients are still poorly studied because of the presence of many involved factors.

Related Articles


A research article to be published on June 7, 2009 in the World Journal of Gastroenterology addresses this question. The research team led by Professor Josep Fuster and Dr. Josep Marti from Hospital Clinic in Barcelona (Spain) reviewed their patients undergoing surgery for colorectal liver metastases from 1994 to 2006 to study the changes during two different time periods. As various studies have shown better operative outcomes and advances in patient selection and treatments in recent times, the article further investigated the results of all these changes on patient survival and cancer recurrence.

The study analyzed prognostic factors and found that patients with extrahepatic disease, high levels of carcinoembriogenic antigen (a commonly used tumor marker for colorectal cancer patients' surveillance) or more than 4 nodules were at risk of a poorer survival. Patient survival at 5-years after surgery was 47%. It was seen that patients in the second time period had more adverse prognostic factors and a shorter hospital stay than in the first period but no differences in overall survival and recurrence were observed between the two periods.

Although prognostic factors for survival and cancer recurrence of patients undergoing surgery for colorectal liver metastases are important for the selection of the best treatment options, improvements in surgical technique and better complementary treatments in recent times allow for the increase in the number of patients benefiting from surgical curative treatment. However, a careful patient selection and the judicious use of other available treatments prior to and after surgery are crucial to improve prognosis in these patients.

Professor Josep Fuster and Dr. Josep Marti are currently working at the Liver Surgery and Transplantation Unit at Hospital Clinic in Barcelona (Spain), a well known Institution for its leading advances and publications in liver and gastrointestinal diseases.


Story Source:

The above story is based on materials provided by World Journal of Gastroenterology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Martí J, Modolo MM, Fuster J, Comas J, Cosa R, Ferrer J, Molina V, Romero J, Fondevila C, Charco R, García-Valdecasas JC. Prognostic factors and time-related changes influence results of colorectal liver metastases surgical treatment: A single-center analysis. World Journal of Gastroenterology, 2009; 15 (21): 2587 DOI: 10.3748/wjg.15.2587

Cite This Page:

World Journal of Gastroenterology. "Advances In Liver Surgery Enable The Prospect Of Curative Treatment For More Patients." ScienceDaily. ScienceDaily, 15 June 2009. <www.sciencedaily.com/releases/2009/06/090615094042.htm>.
World Journal of Gastroenterology. (2009, June 15). Advances In Liver Surgery Enable The Prospect Of Curative Treatment For More Patients. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2009/06/090615094042.htm
World Journal of Gastroenterology. "Advances In Liver Surgery Enable The Prospect Of Curative Treatment For More Patients." ScienceDaily. www.sciencedaily.com/releases/2009/06/090615094042.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins