Featured Research

from universities, journals, and other organizations

Erythropoietin Boosts Brainpower, Researchers Find

Date:
July 8, 2009
Source:
BioMed Central
Summary:
Healthy young mice treated with erythropoietin show lasting improved performance in learning and other higher brain functions. Researchers tested the cognitive effects of the growth factor, finding that it improved the sequential learning and memory components of a complex long-term cognitive task.

Healthy young mice treated with erythropoietin show lasting improved performance in learning and other higher brain functions. Researchers writing in the open access journal BMC Biology tested the cognitive effects of the growth factor, finding that it improved the sequential learning and memory components of a complex long-term cognitive task.

Hannelore Ehrenreich led a team of researchers from the Max Planck Institute of Experimental Medicine in Gφttingen, Germany, who studied the mice. She said, "Erythropoietin has been in clinical use for over 20 years to treat patients with anemic conditions, ranging from renal failure to cancer. It has recently received attention for its apparent ability to improve cognitive function in people with schizophrenia and multiple sclerosis. Here, we sought to investigate erythropoietin's effects in healthy mice".

Ehrenreich and her colleagues tested the effects of erythropoietin on the ability of the mice to learn how to exploit an experimental set-up to receive sugared water. Over a series of learning stages, the mice were trained to get their treat by poking their noses into holes lit by LEDs, rather than into unlit holes, within a time limit. The mice that had been treated with recombinant human erythropoietin were significantly more likely to master the task than those that had not. According to Ehrenreich, "Treated mice showed superior performance in associative, operant and discriminant learning as well as in the initial training phases. Moreover, erythropoietin-treated mice demonstrated better task adaptation and higher performance stability".

The researchers conclude, "Further untangling of molecular mechanisms of erythropoietin action on higher cognitive functions may ultimately open new avenues for prevention strategies and therapeutic interventions in neuropsychiatric diseases".


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ahmed El-Kordi, Konstantin Radyushkin and Hannelore Ehrenreich. Erythropoietin improves operant conditioning and stability of cognitive performance in mice. BMC Biology, 2009; [link]

Cite This Page:

BioMed Central. "Erythropoietin Boosts Brainpower, Researchers Find." ScienceDaily. ScienceDaily, 8 July 2009. <www.sciencedaily.com/releases/2009/07/090707201110.htm>.
BioMed Central. (2009, July 8). Erythropoietin Boosts Brainpower, Researchers Find. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2009/07/090707201110.htm
BioMed Central. "Erythropoietin Boosts Brainpower, Researchers Find." ScienceDaily. www.sciencedaily.com/releases/2009/07/090707201110.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) — The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) — Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com
Condemned Man's US Execution Takes Nearly Two Hours

Condemned Man's US Execution Takes Nearly Two Hours

AFP (July 24, 2014) — America's death penalty debate raged Thursday after it took nearly two hours for Arizona to execute a prisoner who lost a Supreme Court battle challenging the experimental lethal drug cocktail. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Can Watching TV Make You Feel Like A Failure?

Can Watching TV Make You Feel Like A Failure?

Newsy (July 24, 2014) — A study by German researchers claims watching TV while you're stressed out can make you feel guilty and like a failure. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:  

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile iPhone Android Web
          Follow Facebook Twitter Google+
          Subscribe RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins