Featured Research

from universities, journals, and other organizations

Immunotherapy Linked To Lower Risk Of Alzheimer's Disease

Date:
July 21, 2009
Source:
American Academy of Neurology
Summary:
Immunotherapy IVIg treatments, the addition of good antibodies into the blood stream, may hold promise for lowering the risk of Alzheimer's disease and other similar brain disorders, according to new research.

Immunotherapy IVIg treatments, the addition of good antibodies into the blood stream, may hold promise for lowering the risk of Alzheimer's disease and other similar brain disorders, according to research published in the July 21, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology.

Related Articles


"In our study, we looked at the association of the use of intravenous immunoglobulin (IVIg) with the occurrence of Alzheimer's disease. IVIg has been used safely for more than 20 years to treat other diseases but is thought to have an indirect effect on Alzheimer's disease by targeting beta-amyloid, or plaques in the brain," said Howard Fillit, MD, with the Mount Sinai School of Medicine in New York.

For the study, researchers analyzed the medical records of 847 people given at least one treatment of IVIg over four years and 84,700 who were not given IVIg treatment. Participants were treated for immune deficiencies, leukemia or other types of cancer, anemia and other diseases. The records were pulled from a database of 20 million patients age 65 or older developed by SDI Health. Scientists made sure the groups were similar in their risk factors for Alzheimer's disease.

The study found that people who received IVIg for other conditions had a 42-percent lower risk of developing Alzheimer's disease over four years compared to those who did not receive IVIg. Only 2.8 percent of those treated with IVIg developed Alzheimer's disease compared with 4.8 percent of those not treated with immune-based therapy.

"Our study provides evidence that previous IVIg treatments may protect against Alzheimer's disease," said Fillit. "The current Alzheimer's drugs on the market treat the symptoms of the disease. Immunization could treat the underlying cause."

"These findings do not constitute an endorsement of IVIg treatment for Alzheimer's disease. A large scale clinical trial is underway to determine whether IVIg could be an effective treatment for Alzheimer's," researchers said.

The study was supported by Baxter International Inc., a manufacturer of IVIg.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "Immunotherapy Linked To Lower Risk Of Alzheimer's Disease." ScienceDaily. ScienceDaily, 21 July 2009. <www.sciencedaily.com/releases/2009/07/090720163536.htm>.
American Academy of Neurology. (2009, July 21). Immunotherapy Linked To Lower Risk Of Alzheimer's Disease. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2009/07/090720163536.htm
American Academy of Neurology. "Immunotherapy Linked To Lower Risk Of Alzheimer's Disease." ScienceDaily. www.sciencedaily.com/releases/2009/07/090720163536.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) — It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) — More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) — In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) — A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins