Featured Research

from universities, journals, and other organizations

Exercise Benefits Leukemia Patients

Date:
August 3, 2009
Source:
University of North Carolina School of Medicine
Summary:
A new study suggests that exercise may be an effective way to combat the debilitating fatigue that leukemia patients experience.

One of the most bothersome symptoms of leukemia is extreme fatigue, and asking these patients to exercise doesn't sound like a way to help them feel better.

Related Articles


A new study from the University of North Carolina at Chapel Hill indicates that exercise may be a great way to do just that, combating the debilitating fatigue that these patients experience.

In a first-of-its-kind clinical trial, a team of researchers from the Department of Exercise and Sport Science and UNC Lineberger Comprehensive Cancer Center have shown that physical activity can significantly improve symptoms of fatigue and depression, increase cardiovascular endurance and maintain quality of life for adult patients undergoing treatment for leukemia.

A total of 10 patients undergoing treatment participated in the EQUAL (Exercise and Quality of Life in Leukemia/ Lymphoma Patients) study. Each patient was provided with specially-treated exercise equipment to minimize the risk of infection. They participated in an individualized exercise session while in the hospital for the 3-5 weeks of the induction phase of leukemia treatment. The exercise prescription comprised of aerobic and resistance exercises, core exercises, and light stretches tailored to the patient's level of fitness and leukemia symptoms. Upon their discharge from the hospital, each patient received an aerobic- based exercise prescription to use during their 2-week home recovery period.

Before and after the exercise program, the researchers tested key physiological measurements including resting heart rate, blood pressure and hemoglobin, body weight and height, body composition, cardiorespiratory fitness and muscular endurance. Psychological measures were tested using standard scales for assessing fatigue, depression and quality of life in cancer patients. Blood samples were also taken at baseline, mid, and at the conclusion of the study, and analyzed for cytokines, biomarkers of inflammation. The results of the study were recently published in the journal Integrative Cancer Therapies.

"We found that the patients experienced significant reduction in total fatigue and depression scores, as well as improved cardiorespiratory endurance and maintenance of muscular endurance," said Claudio Battaglini, Ph.D., assistant professor of exercise and sport science and UNC Lineberger member.

"This is important because of the numerous side-effects related to cancer treatment, and particularly leukemia treatment, which requires confinement to a hospital room for 4-6 weeks to avoid the risk of infection. We have demonstrated that these patients not only can complete an exercise program in the hospital but that they may receive both physiological and psychological benefits that could assist in their recovery," he added.

EQUAL phase II is in development. The follow-up study will consisted of a randomized clinical-controlled trial to assess the effects on an individualized exercise prescription in acute leukemia patients vs. a group of leukemia patients receiving the usual treatment. If the results prove to be beneficial to patients, the goal of the research team will be to expand the trial by developing a multi-site research program involving other cancer centers throughout North Carolina and around the United States.

Along with Battaglini, study co-authors include professor Anthony Hackney, Ph.D., associate professor Diane Groff, Ed.D., and graduate student Elizabeth Evans from the Department of Exercise and Sport Science. Hackney and Groff are also members of UNC Lineberger Comprehensive Cancer Center, along with nurse consultant Rey Garcia and Thomas Shea, M.D., professor of hematology/oncology and director of the UNC bone marrow transplant program.

This research was supported by a UNC Lineberger Internal Grants Award, a UNC Junior Faculty Development Award, and a UNC Institute of Aging, Stimulus Grant in Aging and made possible due to cooperation by UNC Hospitals.


Story Source:

The above story is based on materials provided by University of North Carolina School of Medicine. Note: Materials may be edited for content and length.


Cite This Page:

University of North Carolina School of Medicine. "Exercise Benefits Leukemia Patients." ScienceDaily. ScienceDaily, 3 August 2009. <www.sciencedaily.com/releases/2009/08/090803083635.htm>.
University of North Carolina School of Medicine. (2009, August 3). Exercise Benefits Leukemia Patients. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2009/08/090803083635.htm
University of North Carolina School of Medicine. "Exercise Benefits Leukemia Patients." ScienceDaily. www.sciencedaily.com/releases/2009/08/090803083635.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins