Featured Research

from universities, journals, and other organizations

Exercise Benefits Leukemia Patients

Date:
August 3, 2009
Source:
University of North Carolina School of Medicine
Summary:
A new study suggests that exercise may be an effective way to combat the debilitating fatigue that leukemia patients experience.

One of the most bothersome symptoms of leukemia is extreme fatigue, and asking these patients to exercise doesn't sound like a way to help them feel better.

A new study from the University of North Carolina at Chapel Hill indicates that exercise may be a great way to do just that, combating the debilitating fatigue that these patients experience.

In a first-of-its-kind clinical trial, a team of researchers from the Department of Exercise and Sport Science and UNC Lineberger Comprehensive Cancer Center have shown that physical activity can significantly improve symptoms of fatigue and depression, increase cardiovascular endurance and maintain quality of life for adult patients undergoing treatment for leukemia.

A total of 10 patients undergoing treatment participated in the EQUAL (Exercise and Quality of Life in Leukemia/ Lymphoma Patients) study. Each patient was provided with specially-treated exercise equipment to minimize the risk of infection. They participated in an individualized exercise session while in the hospital for the 3-5 weeks of the induction phase of leukemia treatment. The exercise prescription comprised of aerobic and resistance exercises, core exercises, and light stretches tailored to the patient's level of fitness and leukemia symptoms. Upon their discharge from the hospital, each patient received an aerobic- based exercise prescription to use during their 2-week home recovery period.

Before and after the exercise program, the researchers tested key physiological measurements including resting heart rate, blood pressure and hemoglobin, body weight and height, body composition, cardiorespiratory fitness and muscular endurance. Psychological measures were tested using standard scales for assessing fatigue, depression and quality of life in cancer patients. Blood samples were also taken at baseline, mid, and at the conclusion of the study, and analyzed for cytokines, biomarkers of inflammation. The results of the study were recently published in the journal Integrative Cancer Therapies.

"We found that the patients experienced significant reduction in total fatigue and depression scores, as well as improved cardiorespiratory endurance and maintenance of muscular endurance," said Claudio Battaglini, Ph.D., assistant professor of exercise and sport science and UNC Lineberger member.

"This is important because of the numerous side-effects related to cancer treatment, and particularly leukemia treatment, which requires confinement to a hospital room for 4-6 weeks to avoid the risk of infection. We have demonstrated that these patients not only can complete an exercise program in the hospital but that they may receive both physiological and psychological benefits that could assist in their recovery," he added.

EQUAL phase II is in development. The follow-up study will consisted of a randomized clinical-controlled trial to assess the effects on an individualized exercise prescription in acute leukemia patients vs. a group of leukemia patients receiving the usual treatment. If the results prove to be beneficial to patients, the goal of the research team will be to expand the trial by developing a multi-site research program involving other cancer centers throughout North Carolina and around the United States.

Along with Battaglini, study co-authors include professor Anthony Hackney, Ph.D., associate professor Diane Groff, Ed.D., and graduate student Elizabeth Evans from the Department of Exercise and Sport Science. Hackney and Groff are also members of UNC Lineberger Comprehensive Cancer Center, along with nurse consultant Rey Garcia and Thomas Shea, M.D., professor of hematology/oncology and director of the UNC bone marrow transplant program.

This research was supported by a UNC Lineberger Internal Grants Award, a UNC Junior Faculty Development Award, and a UNC Institute of Aging, Stimulus Grant in Aging and made possible due to cooperation by UNC Hospitals.


Story Source:

The above story is based on materials provided by University of North Carolina School of Medicine. Note: Materials may be edited for content and length.


Cite This Page:

University of North Carolina School of Medicine. "Exercise Benefits Leukemia Patients." ScienceDaily. ScienceDaily, 3 August 2009. <www.sciencedaily.com/releases/2009/08/090803083635.htm>.
University of North Carolina School of Medicine. (2009, August 3). Exercise Benefits Leukemia Patients. ScienceDaily. Retrieved August 27, 2014 from www.sciencedaily.com/releases/2009/08/090803083635.htm
University of North Carolina School of Medicine. "Exercise Benefits Leukemia Patients." ScienceDaily. www.sciencedaily.com/releases/2009/08/090803083635.htm (accessed August 27, 2014).

Share This




More Health & Medicine News

Wednesday, August 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Predicting Heart Transplant Rejection With a Blood Test

Predicting Heart Transplant Rejection With a Blood Test

Ivanhoe (Aug. 27, 2014) Now a new approach to rejection of donor organs could change the way doctors predict transplant rejection…without expensive, invasive procedures. Video provided by Ivanhoe
Powered by NewsLook.com
Better Braces That Vibrate

Better Braces That Vibrate

Ivanhoe (Aug. 27, 2014) The length of time you have to keep your braces on could be cut in half thanks to a new device that speeds up the process. Video provided by Ivanhoe
Powered by NewsLook.com
Smartphone App Tracks Your Heart Rate

Smartphone App Tracks Your Heart Rate

Ivanhoe (Aug. 27, 2014) A new app that can track your heart rate 24/7 is available for download in your app store and its convenience could save your life. Video provided by Ivanhoe
Powered by NewsLook.com
Stroke in Young Adults

Stroke in Young Adults

Ivanhoe (Aug. 27, 2014) A stroke can happen at any time and affect anyone regardless of age. This mother chose to give her son independence and continue to live a normal life after he had a stroke at 18 years old. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins