Featured Research

from universities, journals, and other organizations

IgM In Urine Acts As Prognostic Indicator In Diabetes

Date:
August 6, 2009
Source:
BioMed Central
Summary:
A marker of the likely course of diabetic nephropathy has been found. An 18-year study has shown that Immunoglobulin M is a reliable predictor of cardiovascular complications in DN patients.

A marker of the likely course of diabetic nephropathy (DN) has been found. An 18-year study has shown that Immunoglobulin M (IgM) is a reliable predictor of cardiovascular complications in DN patients.

Related Articles


Omran Bakoush, MD, PhD, led a team of researchers from Lund University, Sweden, who carried out the research. He said, "To our knowledge, this study is the first to investigate the impact of increased urine IgM excretion on DN disease progression in type 1 diabetic patients. We found that those with increased urinary IgM excretion had a higher mortality from cardiovascular causes, and higher disease progression rate to end-stage renal disease. This association is largely independent of the level of albuminuria".

The researchers followed 139 patients with type 1 diabetes mellitus between 1984 and 2007. Patients with increased urine IgM excretion, measured by ELISA at the beginning of the study, were approximately three times more likely to die or progress to end-stage renal disease. Commenting on these findings, Dr Bakoush said, "These findings may offer a new approach to manage this rapidly increasing patient population. While measurement of albuminuria is routinely used to evaluate and manage patients with diabetes, increased urine IgM excretion would identify more specifically patients at risk for serious cardiovascular complications (death, and renal failure). If increased urine IgM excretion does reflects advanced atherosclerotic vascular disease, clinical trials would be justified to test whether modifying atherosclerotic factors, also decrease mortality and incidence of renal failure in diabetic patients with or without IgM-uria".


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Rafid Tofik, Ole Torffvit, Bengt Rippe and Omran Bakoush. Increased urine IgM excretion predicts cardiovascular events in patients with type 1 diabetes nephropathy. BMC Medicine, (in press) [link]

Cite This Page:

BioMed Central. "IgM In Urine Acts As Prognostic Indicator In Diabetes." ScienceDaily. ScienceDaily, 6 August 2009. <www.sciencedaily.com/releases/2009/08/090803193647.htm>.
BioMed Central. (2009, August 6). IgM In Urine Acts As Prognostic Indicator In Diabetes. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2009/08/090803193647.htm
BioMed Central. "IgM In Urine Acts As Prognostic Indicator In Diabetes." ScienceDaily. www.sciencedaily.com/releases/2009/08/090803193647.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins