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Unlocking The Secret Of The Bladder's Bouncers

Date:
August 25, 2009
Source:
Duke University Medical Center
Summary:
Researchers may have a new way to stop and even prevent the urinary tract infections that plague more than a third of all adults, some of them repeatedly.

Researchers at Duke University Medical Center may have a new way to stop and even prevent the urinary tract infections (UTIs) that plague more than a third of all adults, some of them repeatedly.

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The researchers have discovered how cells within the bladder are able to sense the presence of E. coli bacteria hiding within compartments in the bladder's own cells. This starts a process that then kicks them out.

Knowing how the bladder's own cells sense the bacteria and what they do to expel them are both processes the Duke scientists think they can exploit to do a better job of helping the bladder protect itself. New treatments based on their findings might be able to tackle antibiotic-resistant UTIs and perhaps even bacterial infections in other parts of the body, said Soman Abraham, a professor of pathology at Duke.

The findings appear in the Proceedings of the National Academy of Sciences.


Story Source:

The above story is based on materials provided by Duke University Medical Center. Note: Materials may be edited for content and length.


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Duke University Medical Center. "Unlocking The Secret Of The Bladder's Bouncers." ScienceDaily. ScienceDaily, 25 August 2009. <www.sciencedaily.com/releases/2009/08/090820161331.htm>.
Duke University Medical Center. (2009, August 25). Unlocking The Secret Of The Bladder's Bouncers. ScienceDaily. Retrieved March 4, 2015 from www.sciencedaily.com/releases/2009/08/090820161331.htm
Duke University Medical Center. "Unlocking The Secret Of The Bladder's Bouncers." ScienceDaily. www.sciencedaily.com/releases/2009/08/090820161331.htm (accessed March 4, 2015).

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