Featured Research

from universities, journals, and other organizations

Disclosing Financial Conflicts Of Interest To Research Participants May Not Be Enough

Date:
August 28, 2009
Source:
Johns Hopkins Medical Institutions
Summary:
Disclosure of financial conflicts of interests to potential participants in research is important, but may have a limited role in managing these conflicts, according to a new study.

Disclosure of financial conflicts of interests to potential participants in research is important, but may have a limited role in managing these conflicts, according to a new study by Johns Hopkins, Duke and Wake Forest.

The study's recommendations provide a framework for establishing sound policy and practices for how best to disclose financial conflicts of interests to potential participants in clinical research, said Jeremy Sugarman, M.D., senior author of a paper published in the August 27th issue of The New England Journal of Medicine and the deputy director for medicine at the Berman Institute of Bioethics at Johns Hopkins.

The paper drew on five years of research from the Conflict of Interest Notification Study, (COINS), a $3 million project led by Sugarman and funded by the National Heart, Lung, and Blood Institute of the National Institutes of Health. Overall, COINS gathered information from thousands of patients as well as many clinical trial investigators, and those charged with the ethical oversight of research.

Clinical investigators have long been urged to disclose their financial interests to potential participants in a study through the informed consent process. But in their NEJM paper, the authors questioned what goal this disclosure is hoping to achieve.

Examples of financial interests include corporate funding for the expense of enrolling a patient in a trial or a researcher having a consulting contract or stock ownership with corporate sponsors with a stake in a trial.

"Our study reveals that disclosure to participants by itself is not the remedy that many seek," Sugarman said. "But disclosure may have positive effects on people's satisfaction with and trust in the research process."

The authors recommend that research participants not be the sole decision-makers about the potential risks arising from investigators' financial relationships. They agreed that disclosure during the consent process should be brief and simple, and that trial coordinators should have the information they need to address questions about financial relationships.

Kevin Weinfurt, Ph.D., the lead author of the paper said "multiple studies show that most research participants want to know about investigators' financial relationships, but that this information often doesn't change their minds about enrolling."

The authors said participants likely won't fully understand the nature of investigators' financial interests, but that disclosure encourages transparency, often satisfies participants' perceived right to know, and could foster more trust.

If stock ownership is at play, other management techniques in addition to disclosure should be used. Simply disclosing this information is insufficient the authors said, because research participants are sometimes troubled by investigators' and institutions' equity interests in clinical research.

The authors also agreed that those overseeing conflicts of interest should be explicit about their goals and design plans for managing financial interests that include disclosure requirements toward meeting those goals. The recommendations were offered to investigators, institutional review boards, conflict-of-interest committees and policy makers.

The study was supported by grant from the National Heart, Lung, and Blood Institute.

Other authors are Kevin P. Weinfurt, Ph.D., Joλlle Y. Friedman, M.P.A., and Kevin A. Schulman, M.D., of Duke University and Mark A. Hall, J.D., and Nancy M. P. King, J.D., of Wake Forest University.


Story Source:

The above story is based on materials provided by Johns Hopkins Medical Institutions. Note: Materials may be edited for content and length.


Cite This Page:

Johns Hopkins Medical Institutions. "Disclosing Financial Conflicts Of Interest To Research Participants May Not Be Enough." ScienceDaily. ScienceDaily, 28 August 2009. <www.sciencedaily.com/releases/2009/08/090826191841.htm>.
Johns Hopkins Medical Institutions. (2009, August 28). Disclosing Financial Conflicts Of Interest To Research Participants May Not Be Enough. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2009/08/090826191841.htm
Johns Hopkins Medical Institutions. "Disclosing Financial Conflicts Of Interest To Research Participants May Not Be Enough." ScienceDaily. www.sciencedaily.com/releases/2009/08/090826191841.htm (accessed October 21, 2014).

Share This



More Science & Society News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Traditional Farming Methods Gaining Ground in Mali

Traditional Farming Methods Gaining Ground in Mali

AFP (Oct. 20, 2014) — He is leading a one man agricultural revolution in Mali - Oumar Diatabe uses traditional farming methods to get the most out of his land and is teaching others across the country how to do the same. Duration: 01:44 Video provided by AFP
Powered by NewsLook.com
Your Birth Season Might Determine Your Temperament

Your Birth Season Might Determine Your Temperament

Newsy (Oct. 20, 2014) — A new study says the season you're born in can determine your temperament — and one season has a surprising outcome. Video provided by Newsy
Powered by NewsLook.com
How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) — The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) — Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Science & Society

Business & Industry

Education & Learning

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins