Featured Research

from universities, journals, and other organizations

Weight Gain In Adulthood Associated With Prostate Cancer Risk; Patterns Differ By Ethnicity

Date:
September 2, 2009
Source:
American Association for Cancer Research
Summary:
Body mass in younger and older adulthood, and weight gain between these periods of life, may influence a man's risk for prostate cancer. This risk varies among different ethnic populations, according to results of a new study.

Body mass in younger and older adulthood, and weight gain between these periods of life, may influence a man's risk for prostate cancer. This risk varies among different ethnic populations, according to results of a study in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

"The relationship of certain characteristics, such as body size, with cancer risk may vary across ethnic groups due to the combined influence of both genes and lifestyle," said lead researcher Brenda Y. Hernandez, Ph.D., M.P.H., assistant professor at the Cancer Research Center of Hawaii, University of Hawaii.

Obesity is a risk factor for common cancers like colorectal cancer and breast cancer in post-menopausal women. However, the influence of body size on prostate cancer risk is not entirely understood. Hernandez and colleagues examined this relationship in a multiethnic population consisting of blacks, Japanese, Hispanics, Native Hawaiians and whites, and compared differences among age groups. They used the Multiethnic Cohort, a longitudinal study of men aged 45 to 75 years old established in Hawaii and California from 1993 to 1996.

Results showed that of the 83,879 men who participated in this study, 5,554 were diagnosed with prostate cancer. Overall, men who were overweight or obese by age 21 had a decreased risk of localized and low-grade prostate cancer, according to Hernandez.

Being overweight in older adulthood was associated with increased risk of prostate cancer among white and Native Hawaiian men, but a decreased risk among Japanese men. Excessive weight gain between younger and older adulthood increased the risk of advanced and high-grade prostate cancers in white men and increased the risk of localized and low-grade disease in black men, but decreased the risk of localized prostate cancer in Japanese men.

"Readers of Cancer Epidemiology, Biomarkers & Prevention might initially look at these results and discount them for being inconsistent across the racial/ethnic groups, but they should not," said Elizabeth A. Platz, Sc.D., M.P.H., associate professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health, Baltimore.

Platz stressed the strengths of this study, including that it was conducted prospectively and consisted of large numbers of men in most of the ethnic groups studied. An estimated 30 percent of prostate cancer cases occurred among Japanese men (n=25,275), 25 percent among white men (n=21,311), 27 percent among Hispanic men (n=20,448), 13 percent among black men (n=10,934), and 7 percent among Native Hawaiian men (n=5,921).

"There is no reason to think that the differences in results by ethnicity are explained by bias. Different racial and ethnic populations tend to have differing proportions of fat relative to lean mass and carry their fat mass differently. These differences may be used as a launching point for the next line of research: The nature of the weight gain — amount of fat gained and distribution of the fat gained in association with prostate cancer risk overall, and by stage and grade," added Platz, who is also an editorial board member for Cancer Epidemiology, Biomarkers & Prevention.

This study underscores the importance of investigating cancer etiology in diverse populations and researchers should conduct additional studies.

"These results do not warrant a change in the current public health messages about obesity: Men of normal weight in all racial/ethnic groups should be encouraged to avoid weight gain and men who are overweight and obese should be encouraged to lose weight for good health in general," Platz added.


Story Source:

The above story is based on materials provided by American Association for Cancer Research. Note: Materials may be edited for content and length.


Cite This Page:

American Association for Cancer Research. "Weight Gain In Adulthood Associated With Prostate Cancer Risk; Patterns Differ By Ethnicity." ScienceDaily. ScienceDaily, 2 September 2009. <www.sciencedaily.com/releases/2009/09/090901132802.htm>.
American Association for Cancer Research. (2009, September 2). Weight Gain In Adulthood Associated With Prostate Cancer Risk; Patterns Differ By Ethnicity. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2009/09/090901132802.htm
American Association for Cancer Research. "Weight Gain In Adulthood Associated With Prostate Cancer Risk; Patterns Differ By Ethnicity." ScienceDaily. www.sciencedaily.com/releases/2009/09/090901132802.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins