Featured Research

from universities, journals, and other organizations

Increased Risk Of Birth Defects After PCE Exposure

Date:
September 25, 2009
Source:
BioMed Central
Summary:
Exposure to tetrachloroethylene (also known as perchlorethylene, PCE) may cause congenital birth defects. A study of expectant women exposed to PCE in drinking water found an increased risk of oral clefts and neural tube defects in their children.

Exposure to tetrachloroethylene (also known as perchlorethylene, PCE) may cause congenital birth defects. A study of expectant women exposed to PCE in drinking water, published in BioMed Central's open access journal Environmental Health, found an increased risk of oral clefts and neural tube defects in their children.

Related Articles


Ann Aschengrau, from Boston University School of Public Health, USA, worked with a team of researchers to study the prevalence of birth defects in the children of women from 8 towns in Cape Cod who had been exposed to PCE during the period 1969-1983. She said, "The results suggest that the risk of certain congenital anomalies is increased among the offspring of women who were exposed to PCE-contaminated drinking water around the time of conception".

From the late 1960s until 1980, hundreds of miles of pipe that had been lined with a vinyl coating containing PCE were laid in the area. It wasn't until 1980 that officials realized the danger, creating what the researchers describe as "A vast natural experiment reminiscent of John Snow's cholera investigation in 1854 London." Boston University investigators found that there were 61 children with congenital anomalies among the 1,658 children with some prenatal PCE exposure and 95 children with congenital anomalies among 2,999 children with no prenatal PCE exposure. Prenatal exposure was associated with increases in the risk of oral clefts and neural tube defects (particularly anencephaly).

Speaking about these findings, Aschengrau said, "Because PCE remains a commonly used solvent and frequent contaminant of ground and drinking water supplies, it is important to understand its impact on the developing fetus."


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ann Aschengrau, Janice M Weinberg, Patricia A Janulewicz, Lisa G Gallagher, Michael R Winter, Veronica M Vieira, Thomas F Webster and David M Ozonoff. Prenatal exposure to tetrachloroethylene-contaminated drinking water and the risk of congenital anomalies: a retrospective cohort study. Environmental Health, (in press) [link]

Cite This Page:

BioMed Central. "Increased Risk Of Birth Defects After PCE Exposure." ScienceDaily. ScienceDaily, 25 September 2009. <www.sciencedaily.com/releases/2009/09/090923195108.htm>.
BioMed Central. (2009, September 25). Increased Risk Of Birth Defects After PCE Exposure. ScienceDaily. Retrieved December 21, 2014 from www.sciencedaily.com/releases/2009/09/090923195108.htm
BioMed Central. "Increased Risk Of Birth Defects After PCE Exposure." ScienceDaily. www.sciencedaily.com/releases/2009/09/090923195108.htm (accessed December 21, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, December 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) — It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) — More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) — In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) — The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins