Featured Research

from universities, journals, and other organizations

Increased Risk Of Birth Defects After PCE Exposure

Date:
September 25, 2009
Source:
BioMed Central
Summary:
Exposure to tetrachloroethylene (also known as perchlorethylene, PCE) may cause congenital birth defects. A study of expectant women exposed to PCE in drinking water found an increased risk of oral clefts and neural tube defects in their children.

Exposure to tetrachloroethylene (also known as perchlorethylene, PCE) may cause congenital birth defects. A study of expectant women exposed to PCE in drinking water, published in BioMed Central's open access journal Environmental Health, found an increased risk of oral clefts and neural tube defects in their children.

Ann Aschengrau, from Boston University School of Public Health, USA, worked with a team of researchers to study the prevalence of birth defects in the children of women from 8 towns in Cape Cod who had been exposed to PCE during the period 1969-1983. She said, "The results suggest that the risk of certain congenital anomalies is increased among the offspring of women who were exposed to PCE-contaminated drinking water around the time of conception".

From the late 1960s until 1980, hundreds of miles of pipe that had been lined with a vinyl coating containing PCE were laid in the area. It wasn't until 1980 that officials realized the danger, creating what the researchers describe as "A vast natural experiment reminiscent of John Snow's cholera investigation in 1854 London." Boston University investigators found that there were 61 children with congenital anomalies among the 1,658 children with some prenatal PCE exposure and 95 children with congenital anomalies among 2,999 children with no prenatal PCE exposure. Prenatal exposure was associated with increases in the risk of oral clefts and neural tube defects (particularly anencephaly).

Speaking about these findings, Aschengrau said, "Because PCE remains a commonly used solvent and frequent contaminant of ground and drinking water supplies, it is important to understand its impact on the developing fetus."


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ann Aschengrau, Janice M Weinberg, Patricia A Janulewicz, Lisa G Gallagher, Michael R Winter, Veronica M Vieira, Thomas F Webster and David M Ozonoff. Prenatal exposure to tetrachloroethylene-contaminated drinking water and the risk of congenital anomalies: a retrospective cohort study. Environmental Health, (in press) [link]

Cite This Page:

BioMed Central. "Increased Risk Of Birth Defects After PCE Exposure." ScienceDaily. ScienceDaily, 25 September 2009. <www.sciencedaily.com/releases/2009/09/090923195108.htm>.
BioMed Central. (2009, September 25). Increased Risk Of Birth Defects After PCE Exposure. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2009/09/090923195108.htm
BioMed Central. "Increased Risk Of Birth Defects After PCE Exposure." ScienceDaily. www.sciencedaily.com/releases/2009/09/090923195108.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Artificial Sweetener Could Promote Diabetes

Artificial Sweetener Could Promote Diabetes

Newsy (Sep. 17, 2014) — Doctors once thought artificial sweeteners lacked the health risks of sugar, but a new study says they can impact blood sugar levels the same way. Video provided by Newsy
Powered by NewsLook.com
Ebola Vaccine Trial Gets Underway at Oxford University

Ebola Vaccine Trial Gets Underway at Oxford University

AFP (Sep. 17, 2014) — A healthy British volunteer is to become the first person to receive a new vaccine for the Ebola virus after US President Barack Obama called for action against the epidemic and warned it was "spiralling out of control." Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Obesity Rates Steady Even As Americans' Waistlines Expand

Obesity Rates Steady Even As Americans' Waistlines Expand

Newsy (Sep. 17, 2014) — Researchers are puzzled as to why obesity rates remain relatively stable as average waistlines continue to expand. Video provided by Newsy
Powered by NewsLook.com
President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) — President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins