Featured Research

from universities, journals, and other organizations

Increased Risk Of Birth Defects After PCE Exposure

Date:
September 25, 2009
Source:
BioMed Central
Summary:
Exposure to tetrachloroethylene (also known as perchlorethylene, PCE) may cause congenital birth defects. A study of expectant women exposed to PCE in drinking water found an increased risk of oral clefts and neural tube defects in their children.

Exposure to tetrachloroethylene (also known as perchlorethylene, PCE) may cause congenital birth defects. A study of expectant women exposed to PCE in drinking water, published in BioMed Central's open access journal Environmental Health, found an increased risk of oral clefts and neural tube defects in their children.

Ann Aschengrau, from Boston University School of Public Health, USA, worked with a team of researchers to study the prevalence of birth defects in the children of women from 8 towns in Cape Cod who had been exposed to PCE during the period 1969-1983. She said, "The results suggest that the risk of certain congenital anomalies is increased among the offspring of women who were exposed to PCE-contaminated drinking water around the time of conception".

From the late 1960s until 1980, hundreds of miles of pipe that had been lined with a vinyl coating containing PCE were laid in the area. It wasn't until 1980 that officials realized the danger, creating what the researchers describe as "A vast natural experiment reminiscent of John Snow's cholera investigation in 1854 London." Boston University investigators found that there were 61 children with congenital anomalies among the 1,658 children with some prenatal PCE exposure and 95 children with congenital anomalies among 2,999 children with no prenatal PCE exposure. Prenatal exposure was associated with increases in the risk of oral clefts and neural tube defects (particularly anencephaly).

Speaking about these findings, Aschengrau said, "Because PCE remains a commonly used solvent and frequent contaminant of ground and drinking water supplies, it is important to understand its impact on the developing fetus."


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ann Aschengrau, Janice M Weinberg, Patricia A Janulewicz, Lisa G Gallagher, Michael R Winter, Veronica M Vieira, Thomas F Webster and David M Ozonoff. Prenatal exposure to tetrachloroethylene-contaminated drinking water and the risk of congenital anomalies: a retrospective cohort study. Environmental Health, (in press) [link]

Cite This Page:

BioMed Central. "Increased Risk Of Birth Defects After PCE Exposure." ScienceDaily. ScienceDaily, 25 September 2009. <www.sciencedaily.com/releases/2009/09/090923195108.htm>.
BioMed Central. (2009, September 25). Increased Risk Of Birth Defects After PCE Exposure. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2009/09/090923195108.htm
BioMed Central. "Increased Risk Of Birth Defects After PCE Exposure." ScienceDaily. www.sciencedaily.com/releases/2009/09/090923195108.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) — Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) — The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) — Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) — New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins