Featured Research

from universities, journals, and other organizations

Researchers Validate Technique To Diagnose Tuberculosis In Just One Day

Date:
October 6, 2009
Source:
Andalucía Innova
Summary:
Spanish researchers have validated in patients a technique, originally produced by a German company, capable of diagnosing tuberculosis in only one day and determining whether or not it is resistant to two of the drugs used to treat this disease.

A team headed by Doctor Manuel Casal, head of Microbiology at Reina Sofia Hospital in Cordoba has validated in patients a technique, originally produced by a German company, capable of diagnosing tuberculosis in only one day and determining whether or not it is resistant to two of the drugs used to treat this disease.

Related Articles


This Cordoba laboratory is considered by the Andalusian Government as a benchmark in the study of tuberculosis.

"Fast diagnosis is an important step towards eliminating this disease," affirms the head of the Microbiology Department at Reina Sofia Hospital, whose work group has validated a molecular biology genetics technique capable of detecting within a day, or at the most two, if a patient his suffering from tuberculosis and the mutations resistant to rifampicine and isoniazid, two of the drugs used in the treatment of this disease. "The longer a person suffers the disease without knowing it, the more people can be infected."

According to the Cordoba doctor, this technique does not search for live bacteria, but rather the most important component of these, the nucleic acid, within which a study is made of certain genes "that indicate a resistance mutation. In this way, directly and without having to resort to cultures, it is possible to test a patient suspected of suffering this disease. The test consists in the confrontation of a series of reagents with others, which tells us whether or not the pathology is present." Thanks to this system, "it is possible to obtain the test results the same day, while previous technique required at least 15 days."

At the moment this technique, validated by the doctors in Cordoba, is already being used in the large specialised laboratories of major hospitals and research centres with wide experience in this field.

From 15 days to one month for a diagnosis

Until now, tuberculosis resistances were detected using solid means - cultures of mycobacterium (Mycobacterium tuberculosis) growth - which took a month. Following the culture, the growth was confronted with different drug dilutions to determine whether or not the bacteria were sensitive or resistant to these. As Doctor Casal points out, this process is susceptible to contamination, test failure or contagion, meaning that it has to be carried out in security booths in laboratories.

Bacteria growth is also obtained on liquid mediums, which takes 15 days and also requires stringent security measures. This was the situation up until the introduction of this new technique, which has only one drawback -at the moment, it has only been tested using two of the five front-line drugs used to treat this disease. "Its use needs be extended to world-wide level and to the rest of the drugs."

Five front-line drugs are used to treat this disease, caused by Mycobacterium tuberculosis, with five secondary ones that are used in substitution of the first five when the patient shows resistance to these. It is spread via air from person to person and the minimum treatment lasts six months.


Story Source:

The above story is based on materials provided by Andalucía Innova. Note: Materials may be edited for content and length.


Cite This Page:

Andalucía Innova. "Researchers Validate Technique To Diagnose Tuberculosis In Just One Day." ScienceDaily. ScienceDaily, 6 October 2009. <www.sciencedaily.com/releases/2009/10/091006104621.htm>.
Andalucía Innova. (2009, October 6). Researchers Validate Technique To Diagnose Tuberculosis In Just One Day. ScienceDaily. Retrieved November 1, 2014 from www.sciencedaily.com/releases/2009/10/091006104621.htm
Andalucía Innova. "Researchers Validate Technique To Diagnose Tuberculosis In Just One Day." ScienceDaily. www.sciencedaily.com/releases/2009/10/091006104621.htm (accessed November 1, 2014).

Share This



More Health & Medicine News

Saturday, November 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) — The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) — The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) — New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) — Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins