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Genetic Mutation A Strong Indicator Of Age-related Hearing Loss Risk

Date:
October 7, 2009
Source:
American Academy of Otolaryngology -- Head and Neck Surgery
Summary:
Patients who exhibited a certain genetic mutation of anti-oxidant enzymes are three times more likely to develop age-related hearing loss, according to new research.

Patients who exhibited a certain genetic mutation of anti-oxidant enzymes are three times more likely to develop age-related hearing loss (ARHL), according to new research presented at the 2009 American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) Annual Meeting & OTO EXPO, in San Diego, CA.

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The study, which collected DNA samples from 55 patients with ARHL, indicated that there exists a significant correlation between the presence of a mutation of the GSTT1 gene, and age-related hearing loss. Conversely, there were no associations linked to the NAT2 gene.

Anti-oxidant enzymes and their deficiencies have also been implicated as contributors to diseases such as cancer and cardiovascular disease.


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The above story is based on materials provided by American Academy of Otolaryngology -- Head and Neck Surgery. Note: Materials may be edited for content and length.


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American Academy of Otolaryngology -- Head and Neck Surgery. "Genetic Mutation A Strong Indicator Of Age-related Hearing Loss Risk." ScienceDaily. ScienceDaily, 7 October 2009. <www.sciencedaily.com/releases/2009/10/091006134814.htm>.
American Academy of Otolaryngology -- Head and Neck Surgery. (2009, October 7). Genetic Mutation A Strong Indicator Of Age-related Hearing Loss Risk. ScienceDaily. Retrieved April 18, 2015 from www.sciencedaily.com/releases/2009/10/091006134814.htm
American Academy of Otolaryngology -- Head and Neck Surgery. "Genetic Mutation A Strong Indicator Of Age-related Hearing Loss Risk." ScienceDaily. www.sciencedaily.com/releases/2009/10/091006134814.htm (accessed April 18, 2015).

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