Featured Research

from universities, journals, and other organizations

New Method To Coax Retinal Cells From Stem Cells

Date:
October 21, 2009
Source:
Society for Neuroscience
Summary:
Researchers have developed a new method for identifying retinal precursor cells derived from human embryonic stem cells (those from embryonic tissue) and induced pluripotent stem cells (those from adult skin cells). These precursor cells represent the earliest stages of retinal development. The new method results in a greater yield of retinal cells from stem cells and could be used to better understand disease processes and realize effective treatments for eye disorders.

Researchers have developed a new method for identifying retinal precursor cells derived from human embryonic stem cells (those from embryonic tissue) and induced pluripotent stem cells (those from adult skin cells). These precursor cells represent the earliest stages of retinal development. The new method results in a greater yield of retinal cells from stem cells and could be used to better understand disease processes and realize effective treatments for eye disorders.

Related Articles


The findings were presented at Neuroscience 2009, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

Problems associated with retinal degenerative diseases are due to the injury and death of neurons, or support cells that can't regenerate. The cell types primarily affected are the light-sensing rod and cone photoreceptors and the adjacent retinal pigment epithelium, which maintains proper photoreceptor health and function. If these cells could be replaced or bypassed, sight could be restored.

"So far, a number of human cell sources have been examined to see if they produce multiple retinal cell types, but most candidates have proven inadequate," said Jason S. Meyer, PhD, at University of Wisconsin, the study's lead author. "In comparison, human stem cells have produced cells that are clearly of a retinal nature."

When the stem cells were isolated and matured, specific retinal cell types could be identified, including photoreceptors and retinal pigment epithelium. Using this new system, the authors could regulate the production of certain cell types by adding or removing particular compounds to the cells. "This ability could aid in the discovery of new therapeutic approaches to a variety of disorders affecting the retina," Meyer said. "These findings could lead to treatments for other neurological disorders, in addition to eye diseases."

Research was supported by the National Eye Institute, the Foundation Fighting Blindness, the Lincy Foundation, and the Retina Research Foundation.


Story Source:

The above story is based on materials provided by Society for Neuroscience. Note: Materials may be edited for content and length.


Cite This Page:

Society for Neuroscience. "New Method To Coax Retinal Cells From Stem Cells." ScienceDaily. ScienceDaily, 21 October 2009. <www.sciencedaily.com/releases/2009/10/091021014533.htm>.
Society for Neuroscience. (2009, October 21). New Method To Coax Retinal Cells From Stem Cells. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2009/10/091021014533.htm
Society for Neuroscience. "New Method To Coax Retinal Cells From Stem Cells." ScienceDaily. www.sciencedaily.com/releases/2009/10/091021014533.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins