Featured Research

from universities, journals, and other organizations

New Method To Coax Retinal Cells From Stem Cells

Date:
October 21, 2009
Source:
Society for Neuroscience
Summary:
Researchers have developed a new method for identifying retinal precursor cells derived from human embryonic stem cells (those from embryonic tissue) and induced pluripotent stem cells (those from adult skin cells). These precursor cells represent the earliest stages of retinal development. The new method results in a greater yield of retinal cells from stem cells and could be used to better understand disease processes and realize effective treatments for eye disorders.

Researchers have developed a new method for identifying retinal precursor cells derived from human embryonic stem cells (those from embryonic tissue) and induced pluripotent stem cells (those from adult skin cells). These precursor cells represent the earliest stages of retinal development. The new method results in a greater yield of retinal cells from stem cells and could be used to better understand disease processes and realize effective treatments for eye disorders.

The findings were presented at Neuroscience 2009, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

Problems associated with retinal degenerative diseases are due to the injury and death of neurons, or support cells that can't regenerate. The cell types primarily affected are the light-sensing rod and cone photoreceptors and the adjacent retinal pigment epithelium, which maintains proper photoreceptor health and function. If these cells could be replaced or bypassed, sight could be restored.

"So far, a number of human cell sources have been examined to see if they produce multiple retinal cell types, but most candidates have proven inadequate," said Jason S. Meyer, PhD, at University of Wisconsin, the study's lead author. "In comparison, human stem cells have produced cells that are clearly of a retinal nature."

When the stem cells were isolated and matured, specific retinal cell types could be identified, including photoreceptors and retinal pigment epithelium. Using this new system, the authors could regulate the production of certain cell types by adding or removing particular compounds to the cells. "This ability could aid in the discovery of new therapeutic approaches to a variety of disorders affecting the retina," Meyer said. "These findings could lead to treatments for other neurological disorders, in addition to eye diseases."

Research was supported by the National Eye Institute, the Foundation Fighting Blindness, the Lincy Foundation, and the Retina Research Foundation.


Story Source:

The above story is based on materials provided by Society for Neuroscience. Note: Materials may be edited for content and length.


Cite This Page:

Society for Neuroscience. "New Method To Coax Retinal Cells From Stem Cells." ScienceDaily. ScienceDaily, 21 October 2009. <www.sciencedaily.com/releases/2009/10/091021014533.htm>.
Society for Neuroscience. (2009, October 21). New Method To Coax Retinal Cells From Stem Cells. ScienceDaily. Retrieved April 20, 2014 from www.sciencedaily.com/releases/2009/10/091021014533.htm
Society for Neuroscience. "New Method To Coax Retinal Cells From Stem Cells." ScienceDaily. www.sciencedaily.com/releases/2009/10/091021014533.htm (accessed April 20, 2014).

Share This



More Health & Medicine News

Sunday, April 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins