Featured Research

from universities, journals, and other organizations

Cognitive Problems Are Direct Result Of Cocaine Exposure, New Animal Research Suggests

Date:
October 23, 2009
Source:
Society for Neuroscience
Summary:
New animal studies suggest that memory and other cognitive problems experienced by cocaine-addicted people can result directly from the cocaine abuse in addition to pre-existing traits or lifestyle factors.

New animal studies suggest that memory and other cognitive problems experienced by cocaine-addicted people can result directly from the cocaine abuse in addition to pre-existing traits or lifestyle factors.

Related Articles


The findings were presented at Neuroscience 2009, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

"Our results clearly demonstrate the negative impact that even limited access to cocaine can have on cognitive function," said senior author Charles W. Bradberry, PhD, of the University of Pittsburgh. "These findings may lead to the development of therapies for cognitive impairments as a way to improve addiction treatment."

Cocaine users display a range of cognitive deficits, including problems with decision-making, planning, and memory. The greater these deficits, the more likely treatment will fail. The current finding is part of a multi-year longitudinal study of cognitive assessment in cocaine-exposed rhesus monkeys, which offer an ideal model for study because their brain structure and function are similar to that of humans.

For the study, 14 animals were trained to perform two tasks on a touch screen. One test first assessed how well the animals learned to associate pictures with rewards and then measured cognitive flexibility by reversing high- and low-reward pictures. The other task was a visual working memory task, in which animals had to remember an abstract stimulus for varying periods of delay. After initial training they were separated into two groups, with one group self-administering cocaine on Tuesdays through Fridays. Cognitive testing for both groups was conducted on Mondays, after the cocaine-administering animals had been drug-free for about 72 hours.

The animals showed impairments in learning, cognitive flexibility, and, to a lesser degree, working memory. "The types of errors suggest that poor attention and distractibility were significant contributors to the deficits, for they were similar to those made on cognitive tasks by people with attentional deficit disorders," Bradberry said. His lab plans to investigate whether the brain mechanisms that lead to impaired attention in people with attention deficit disorders may be causing similar problems in people chronically addicted to cocaine.

Research was supported by the Veteran's Administration Medical Research Service and the National Institute on Drug Abuse.


Story Source:

The above story is based on materials provided by Society for Neuroscience. Note: Materials may be edited for content and length.


Cite This Page:

Society for Neuroscience. "Cognitive Problems Are Direct Result Of Cocaine Exposure, New Animal Research Suggests." ScienceDaily. ScienceDaily, 23 October 2009. <www.sciencedaily.com/releases/2009/10/091023102428.htm>.
Society for Neuroscience. (2009, October 23). Cognitive Problems Are Direct Result Of Cocaine Exposure, New Animal Research Suggests. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2009/10/091023102428.htm
Society for Neuroscience. "Cognitive Problems Are Direct Result Of Cocaine Exposure, New Animal Research Suggests." ScienceDaily. www.sciencedaily.com/releases/2009/10/091023102428.htm (accessed October 25, 2014).

Share This



More Mind & Brain News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Academic Scandal Shocks UNC

Academic Scandal Shocks UNC

AP (Oct. 23, 2014) A scandal involving bogus classes and inflated grades at the University of North Carolina was bigger than previously reported, a new investigation found. (Oct. 23) Video provided by AP
Powered by NewsLook.com
Working Mother Getaway: Beaches Turks & Caicos

Working Mother Getaway: Beaches Turks & Caicos

Working Mother (Oct. 22, 2014) Feast your eyes on this gorgeous family-friendly resort. Video provided by Working Mother
Powered by NewsLook.com
What Your Favorite Color Says About You

What Your Favorite Color Says About You

Buzz60 (Oct. 22, 2014) We all have one color we love to wear, and believe it or not, your color preference may reveal some of your character traits. In celebration of National Color Day, Krystin Goodwin (@kyrstingoodwin) highlights what your favorite colors may say about you. Video provided by Buzz60
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins