Featured Research

from universities, journals, and other organizations

High-definition Colonoscopy Detects More Polyps, Researchers Say

Date:
October 31, 2009
Source:
Mayo Clinic
Summary:
High-definition colonoscopy is much more sensitive than standard colonoscopy in finding polyps that could morph into cancer, say researchers.

High-definition (HD) colonoscopy is much more sensitive than standard colonoscopy in finding polyps that could morph into cancer, say researchers at the Mayo Clinic campus in Florida.

They say their findings, presented today at the annual meeting of the American College of Gastroenterology in San Diego, Calif., are not only important because a large group (2,430) of patients participated, but they resulted from the only study to date that has compared these two methods in a general clinical practice setting, among all the patients who needed a colonoscopy and with all the physicians who performed it.

"There hasn't been a definitive trial to see whether high-definition colonoscopy detects more polyps or not, and this was a natural experiment, designed to ask if use of one endoscope or another makes a difference in day-to-day clinical practice," says the study's senior investigator, gastroenterologist Michael Wallace, M.D., a professor of medicine at the College of Medicine, Mayo Clinic.

"Based on these results, it appears that high-definition colonoscopy detects more precancerous polyps," he says. The findings are being presented by Anna Buchner, M.D., who led the research during a fellowship at Mayo Clinic in Florida. She is now at the University of Pennsylvania.

This study was conducted between September 2006 and December 2007 when Mayo Clinic in Florida was switching its six colonoscopy procedure rooms from standard colonoscopy endoscopes to high-definition endoscopes.

An endoscope is the lighted tube inserted into the colon and rectum to look for, and remove, polyps. A high-definition endoscope uses both a high-definition video chip and HD monitors (like HD television) that increase the resolution of the image, Dr. Wallace says.

Patients were not assigned to one scope or the other. Instead, they were placed in whatever room was available and assigned a gastroenterologist who was on duty at the time. "So there was a natural randomization of patients to either standard or high-definition endoscopes, and physicians were not able to cherry-pick their patients," Dr. Wallace says. "No doctors used high definition more than any other and, in this way, you can eliminate most of the variables that can bias results of a clinical trial."

Researchers found that the rate of detection of adenomas -- polyps that are likely to become cancerous -- was 29 percent among patients who were scanned with high-definition endoscopes, versus 24 percent for those in which standard endoscopes were used.

"That is an increase of 20 percent," Dr. Wallace says. "While that may seem small, in light of the 14 million colonoscopies that are performed each year, even small differences add up to important improvements."

All three Mayo Clinic sites (Florida, Minnesota, and Arizona) now only use high-definition endoscopes to perform colonoscopies, Dr. Wallace says. Many clinics in the country have both kinds of endoscopes "so it will not be that hard to move to the newer, and better, technology," he says.

The study was funded by Mayo Clinic, and the authors declare no conflict of interest nor do they endorse the products mentioned in the study. Dr. Wallace did not receive any funds for this study from the company that produced the products evaluated.


Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Cite This Page:

Mayo Clinic. "High-definition Colonoscopy Detects More Polyps, Researchers Say." ScienceDaily. ScienceDaily, 31 October 2009. <www.sciencedaily.com/releases/2009/10/091028134626.htm>.
Mayo Clinic. (2009, October 31). High-definition Colonoscopy Detects More Polyps, Researchers Say. ScienceDaily. Retrieved April 21, 2014 from www.sciencedaily.com/releases/2009/10/091028134626.htm
Mayo Clinic. "High-definition Colonoscopy Detects More Polyps, Researchers Say." ScienceDaily. www.sciencedaily.com/releases/2009/10/091028134626.htm (accessed April 21, 2014).

Share This



More Health & Medicine News

Monday, April 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins