Featured Research

from universities, journals, and other organizations

Additional, Specialized Radiation Not Necessary For Some Women After Mastectomy

Date:
November 2, 2009
Source:
American Society for Radiation Oncology
Summary:
After mastectomy, breast cancer patients who receive radiation treatment to the lymph nodes located behind the breast bone do not live longer than those who do not receive radiation to this hard-to-treat area, according to a randomized 10-year study.

After mastectomy, breast cancer patients who receive radiation treatment to the lymph nodes located behind the breast bone do not live longer than those who do not receive radiation to this hard-to-treat area, according to a randomized 10-year study presented at the plenary session, November 2, 2009, at the 51st Annual Meeting of the American Society for Radiation Oncology (ASTRO).

Related Articles


Breast cancer that is located in an internal, central location in the breast area, and larger tumors that have spread to the lymph nodes located under the arm (axillary) and just above the collar bone (supraclavicular), are more likely to spread to the internal mammary lymph nodes that are located behind the breast bone.

The type of external beam radiation treament used to treat these patients is called internal mammary chain radiation treatment, or IMC-RT. It is challenging to deliver the proper dose of radiation to the internal mammary chain because it is hard to define its exact location and to protect critical organs, such as the heart and lung.

"This is the first study that answers the important question of whether radiation to the internal mammary chain lymph nodes benefit these patients after 10 years of follow-up," Pascale Romestaing, M.D., lead author of the study and a radiation oncologist at Centre de Radiothιrapie Mermoz in Lyon, France said. "Our findings clearly show that it does not affect overall survival. These women still need radiation treatments -- just not additional radiation to these specialized cells."

During external beam radiation therapy, a beam (or multiple beams) of radiation is directed through the skin to the cancer and the immediate surrounding area in order to destroy the main tumor and any nearby cancer cells. The treatments are outpatient and generally painless, much like receiving an X-ray.

The multicenter randomized trial involved 1,334 women newly-diagnosed with stage 1 or 2 breast cancer who had undergone a mastectomy, or surgery to remove a breast. Patients had either cancer that had spread to the axillary lymph nodes or their original tumor was in an internal, central location in the breast area. While all patients received radiation to the chest wall and supraclavicular lymph nodes, one-half of the patients were randomized to also receive the specialized IMC radiation treatment.

After 10 years, researchers found no significant differences in survival rates between the group who received IMC radiation treatment (63 percent) and those who did not (60 percent). The study also found no differences in survival for patients in the study who were analyzed in subgroups. These groups included whether or not their cancer had spread to their lymph nodes, where their original tumor was located, and whether they also underwent chemotherapy or hormone therapy at the same time they had radiation treatment.


Story Source:

The above story is based on materials provided by American Society for Radiation Oncology. Note: Materials may be edited for content and length.


Cite This Page:

American Society for Radiation Oncology. "Additional, Specialized Radiation Not Necessary For Some Women After Mastectomy." ScienceDaily. ScienceDaily, 2 November 2009. <www.sciencedaily.com/releases/2009/11/091102103332.htm>.
American Society for Radiation Oncology. (2009, November 2). Additional, Specialized Radiation Not Necessary For Some Women After Mastectomy. ScienceDaily. Retrieved December 17, 2014 from www.sciencedaily.com/releases/2009/11/091102103332.htm
American Society for Radiation Oncology. "Additional, Specialized Radiation Not Necessary For Some Women After Mastectomy." ScienceDaily. www.sciencedaily.com/releases/2009/11/091102103332.htm (accessed December 17, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, December 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) — Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) — Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Flu Outbreak Closing Schools in Ohio

Flu Outbreak Closing Schools in Ohio

AP (Dec. 17, 2014) — A wave of flu illnesses has forced some Ohio schools to shut down over the past week. State officials confirmed one pediatric flu-related death, a 15-year-old girl in southern Ohio. (Dec. 17) Video provided by AP
Powered by NewsLook.com
Yoga Could Be As Beneficial For The Heart As Walking, Biking

Yoga Could Be As Beneficial For The Heart As Walking, Biking

Newsy (Dec. 17, 2014) — Yoga can help your weight, blood pressure, cholesterol and heart just as much as biking and walking does, a new study suggests. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins