Featured Research

from universities, journals, and other organizations

PET Imaging Before Radiation Not Ideal For Determining Boost Radiation Doses

Date:
November 3, 2009
Source:
Thomas Jefferson University
Summary:
Positron emission tomography imaging of non-small cell lung cancer prior to receiving radiation therapy should not be the basis for determining areas that may benefit from higher doses of radiation, according to new research.

Positron emission tomography (PET) imaging of non-small cell lung cancer prior to receiving radiation therapy should not be the basis for determining areas that may benefit from higher doses of radiation, according to research presented by investigators at Thomas Jefferson University Hospital at the 51st ASTRO Annual Meeting (Abstract #2583/B-186).

Some studies suggest that areas that have the highest amount of hypermetabolic activity on PET scan before treatment are the areas most likely to have increased activity after treatment, according to Nitin Ohri, M.D., a resident in Radiation Oncology at Thomas Jefferson University Hospital. Dr. Ohri analyzed this theory in the Jefferson patient population.

"Investigators are looking to PET imaging find ways to predict if any part of the tumor would benefit from a higher radiation dose," Dr. Ohri said. "I wanted to see if residual activity on a scan after treatment correlates with the activity pattern on a scan done before treatment."

Dr. Ohri looked at the PET scans of 43 patients, of which 15 had significant activity on the scans both before and after treatment. He set up a coordinate system that divided tumors into nine regions or 17 regions for larger tumors. He then correlated the activity in the regions both before and after treatment.

He found that in some patients, the activity pattern was in similar regions before and after treatment. However, there were some patients who showed activity in completely different areas after treatment than there was before treatment.

"It's not sufficient to increase the dose to areas that are especially active on PET imaging before treatment and expect that to improve the control rate," Dr. Ohri said. "It may be more appropriate to do a scan halfway through treatment and plan additional radiation dose around that."


Story Source:

The above story is based on materials provided by Thomas Jefferson University. Note: Materials may be edited for content and length.


Cite This Page:

Thomas Jefferson University. "PET Imaging Before Radiation Not Ideal For Determining Boost Radiation Doses." ScienceDaily. ScienceDaily, 3 November 2009. <www.sciencedaily.com/releases/2009/11/091103102238.htm>.
Thomas Jefferson University. (2009, November 3). PET Imaging Before Radiation Not Ideal For Determining Boost Radiation Doses. ScienceDaily. Retrieved October 2, 2014 from www.sciencedaily.com/releases/2009/11/091103102238.htm
Thomas Jefferson University. "PET Imaging Before Radiation Not Ideal For Determining Boost Radiation Doses." ScienceDaily. www.sciencedaily.com/releases/2009/11/091103102238.htm (accessed October 2, 2014).

Share This



More Health & Medicine News

Thursday, October 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Might Not Be Out Of Control In U.S., But Coverage Is

Ebola Might Not Be Out Of Control In U.S., But Coverage Is

Newsy (Oct. 2, 2014) Coverage of the lone Ebola patient discovered in Texas has U.S. media in a frenzy — but does the coverage match the reality? Video provided by Newsy
Powered by NewsLook.com
US Hunts Contacts of Ebola Patient, Including Children

US Hunts Contacts of Ebola Patient, Including Children

AFP (Oct. 2, 2014) Health officials in Texas on Wednesday scoured the Dallas area for people, including schoolchildren, who came in contact with a Liberian man who was diagnosed with Ebola in the United States. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Study Says Losing Sense Of Smell Can Indicate Death

Study Says Losing Sense Of Smell Can Indicate Death

Newsy (Oct. 2, 2014) Researchers found elderly adults with a poor sense of smell are more likely to die within five years. Video provided by Newsy
Powered by NewsLook.com
Pregnancy Spacing Could Have Big Impact On Autism Risks

Pregnancy Spacing Could Have Big Impact On Autism Risks

Newsy (Oct. 1, 2014) A new study says children born less than one year and more than five years after a sibling can have an increased risk for autism. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins