Featured Research

from universities, journals, and other organizations

PET Imaging Before Radiation Not Ideal For Determining Boost Radiation Doses

Date:
November 3, 2009
Source:
Thomas Jefferson University
Summary:
Positron emission tomography imaging of non-small cell lung cancer prior to receiving radiation therapy should not be the basis for determining areas that may benefit from higher doses of radiation, according to new research.

Positron emission tomography (PET) imaging of non-small cell lung cancer prior to receiving radiation therapy should not be the basis for determining areas that may benefit from higher doses of radiation, according to research presented by investigators at Thomas Jefferson University Hospital at the 51st ASTRO Annual Meeting (Abstract #2583/B-186).

Related Articles


Some studies suggest that areas that have the highest amount of hypermetabolic activity on PET scan before treatment are the areas most likely to have increased activity after treatment, according to Nitin Ohri, M.D., a resident in Radiation Oncology at Thomas Jefferson University Hospital. Dr. Ohri analyzed this theory in the Jefferson patient population.

"Investigators are looking to PET imaging find ways to predict if any part of the tumor would benefit from a higher radiation dose," Dr. Ohri said. "I wanted to see if residual activity on a scan after treatment correlates with the activity pattern on a scan done before treatment."

Dr. Ohri looked at the PET scans of 43 patients, of which 15 had significant activity on the scans both before and after treatment. He set up a coordinate system that divided tumors into nine regions or 17 regions for larger tumors. He then correlated the activity in the regions both before and after treatment.

He found that in some patients, the activity pattern was in similar regions before and after treatment. However, there were some patients who showed activity in completely different areas after treatment than there was before treatment.

"It's not sufficient to increase the dose to areas that are especially active on PET imaging before treatment and expect that to improve the control rate," Dr. Ohri said. "It may be more appropriate to do a scan halfway through treatment and plan additional radiation dose around that."


Story Source:

The above story is based on materials provided by Thomas Jefferson University. Note: Materials may be edited for content and length.


Cite This Page:

Thomas Jefferson University. "PET Imaging Before Radiation Not Ideal For Determining Boost Radiation Doses." ScienceDaily. ScienceDaily, 3 November 2009. <www.sciencedaily.com/releases/2009/11/091103102238.htm>.
Thomas Jefferson University. (2009, November 3). PET Imaging Before Radiation Not Ideal For Determining Boost Radiation Doses. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2009/11/091103102238.htm
Thomas Jefferson University. "PET Imaging Before Radiation Not Ideal For Determining Boost Radiation Doses." ScienceDaily. www.sciencedaily.com/releases/2009/11/091103102238.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins