Featured Research

from universities, journals, and other organizations

Laser surgery does not appear to have long-term effects on corneal cells

Date:
November 12, 2009
Source:
JAMA and Archives Journals
Summary:
Laser eye surgery to correct vision problems does not appear to be associated with lasting changes to cells lining the inside of the cornea at nine years after the procedure, according to a new report.

Laser eye surgery to correct vision problems does not appear to be associated with lasting changes to cells lining the inside of the cornea at nine years after the procedure, according to a report in the November issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

Two types of laser surgery -- photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) -- are often used to correct refractive errors such as nearsightedness, according to background information in the article. Little is known about how these procedures affect the cornea, the transparent membrane covering the eye, on the cellular level over the long term.

Sanjay V. Patel, M.D., and William M. Bourne, M.D., of Mayo Clinic, Rochester, Minn., studied 29 eyes of 16 patients who had undergone LASIK or PRK. Photographs of the cells lining the cornea (endothelial cells) were taken and analyzed before and nine years after surgery. The annual rate of corneal endothelial cell loss in the eyes of patients who had had surgery was compared with those of 42 eyes that had not undergone either procedure.

Nine years after surgery, the density of cells lining the cornea had decreased by 5.3 percent from their preoperative state. However, the average annual rate of cell loss (0.6 percent) was the same in corneas of eyes that were operated on and those that were not.

"Our results support the findings of numerous short-term studies that found no significant endothelial cell loss after LASIK and PRK," the authors write.

"The importance of the findings in our study relates to using corneas that have undergone LASIK or PRK as donor tissue," they conclude. "Our findings of no difference in endothelial cell loss after keratorefractive surgery compared with normal eyes suggests that corneas after keratorefractive surgery should be suitable for posterior lamellar keratoplasty," a surgical treatment for corneal dysfunction that involves donor tissue.

This study was supported by a grant from the National Institutes of Health, by Research to Prevent Blindness Inc., and by the Mayo Foundation.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. Patel et al. Corneal Endothelial Cell Loss 9 Years After Excimer Laser Keratorefractive Surgery. Archives of Ophthalmology, 2009; 127 (11): 1423 DOI: 10.1001/archophthalmol.2009.192

Cite This Page:

JAMA and Archives Journals. "Laser surgery does not appear to have long-term effects on corneal cells." ScienceDaily. ScienceDaily, 12 November 2009. <www.sciencedaily.com/releases/2009/11/091109173718.htm>.
JAMA and Archives Journals. (2009, November 12). Laser surgery does not appear to have long-term effects on corneal cells. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2009/11/091109173718.htm
JAMA and Archives Journals. "Laser surgery does not appear to have long-term effects on corneal cells." ScienceDaily. www.sciencedaily.com/releases/2009/11/091109173718.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Newsy (July 23, 2014) An 8-year-old boy helped his younger brother, who has a rare genetic condition that's confined him to a wheelchair, finish a triathlon. Video provided by Newsy
Powered by NewsLook.com
Thousands Who Can't Afford Medical Care Flock to Free US Clinic

Thousands Who Can't Afford Medical Care Flock to Free US Clinic

AFP (July 23, 2014) America may be the world’s richest country, but in terms of healthcare, the World Health Organisation ranks it 37th. Thousands turned out for a free clinic run by "Remote Area Medical" with a visit from the Governor of Virginia. Duration: 2:40 Video provided by AFP
Powered by NewsLook.com
Stone Fruit Listeria Scare Causes Sweeping Recall

Stone Fruit Listeria Scare Causes Sweeping Recall

Newsy (July 22, 2014) The Wawona Packing Company has issued a voluntary recall on the stone fruit it distributes due to a possible Listeria outbreak. Video provided by Newsy
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins