Featured Research

from universities, journals, and other organizations

Hope for patients with type 2 diabetes

Date:
December 4, 2009
Source:
Saint Louis University
Summary:
The outlook for individuals with type 2 diabetes and coronary artery disease is not as grim as originally believed, according to new research.

The outlook for individuals with type 2 diabetes and coronary artery disease is not as grim as originally believed, according to new Saint Louis University research published in Circulation, the Journal of the American Heart Association.

"Our research found that people with type 2 diabetes and heart disease have a more favorable prognosis with proper medical care and management of risk factors, including cholesterol, blood pressure, high blood sugar levels and smoking than previously thought," said Bernard R. Chaitman, M.D., professor of medicine and cardiologist at Saint Louis University School of Medicine and a lead investigator of the study.

"This goes against common beliefs among many physicians that these patients die most commonly of cardiac causes and gives us a lot of hope."

The goal of the Bypass Angioplasty Revasularization Investigation 2 Diabetes (BARI 2D) trial was to examine how deadly heart disease is in individuals with type 2 diabetes and to identify the best treatment options for these patients, including whether artery revascularization via an angioplasty procedure or bypass surgery is necessary.

In total, 2.368 study participants were followed for five years. All study participants received the treatment recommended by their physician, as well as intensive medical therapy, including medication for cholesterol, blood pressure, diabetes, and lifestyle changes such as weight management and smoking cessation counseling.

The research found that individuals with mild to moderate coronary heart disease, who were treated with intensive medical therapy alone, were no more likely to die from a heart problem after five years than those who also had an angioplasty procedure, which clears artery blockage by inserting a balloon in the artery and then inflating it. After five years, 4 to 5 percent of these patients died from a heart attack or related heart disease.

For individuals with more extensive heart disease, however, coronary bypass surgery, in addition to intensive medical therapy, significantly decreased the risk of heart attacks and cardiac-related deaths. Sixteen percent of patients who received bypass surgery either died or had a heart attack within five years compared to 22 percent of patients who received intensive medical therapy alone.

According to Chaitman, individuals with more severe and extensive coronary blockage are more likely to experience a heart attack without prompt bypass surgery. Heart attacks increase the risk of death five to eight times more than in individuals without a heart attack .

"Our primary goal always is to prevent heart attacks from occurring; however, our research found that angioplasty is not always necessary in preventing a heart attack or cardiac-related death just because a blocked artery is present. Patients with type 2 diabetes and heart disease need to have a frank discussion with their doctors about their treatment options and what's best for their individual case," Chaitman said.

The BARI 2D trial was funded by the national Heart, Lung and Blood Institute and the National Institute of Diabetes and Digestive and Kidney Diseases.

Study co-authors include Regina M Hardison, M.S., (University of Pittsburgh), Dale Adler, M.D., (Brigham and Women's Hospital), Suzanne Gebhart, M.D., (Emory University), Mary Grogan, R.N., (Brown University), Salvador Ocampo, M.D., (Mexican Institute of Social Security in Mexico), George Sopko, M.D., (National Institutes of Health); Jose A. Ramires, M.D., (University of Sao Paula Heart Institute in Brazil), David Schneider, M.D., (University of Vermont) and Robert L. Frye, M.D., (Mayo Clinic).


Story Source:

The above story is based on materials provided by Saint Louis University. Note: Materials may be edited for content and length.


Cite This Page:

Saint Louis University. "Hope for patients with type 2 diabetes." ScienceDaily. ScienceDaily, 4 December 2009. <www.sciencedaily.com/releases/2009/12/091203091910.htm>.
Saint Louis University. (2009, December 4). Hope for patients with type 2 diabetes. ScienceDaily. Retrieved August 23, 2014 from www.sciencedaily.com/releases/2009/12/091203091910.htm
Saint Louis University. "Hope for patients with type 2 diabetes." ScienceDaily. www.sciencedaily.com/releases/2009/12/091203091910.htm (accessed August 23, 2014).

Share This




More Health & Medicine News

Saturday, August 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Newsy (Aug. 21, 2014) An experimental drug used to treat Marburg virus in rhesus monkeys could give new insight into a similar treatment for Ebola. Video provided by Newsy
Powered by NewsLook.com
Two US Ebola Patients Leave Hospital Free of the Disease

Two US Ebola Patients Leave Hospital Free of the Disease

AFP (Aug. 21, 2014) Two American missionaries who were sickened with Ebola while working in Liberia and were treated with an experimental drug are doing better and have left the hospital, doctors say on August 21, 2014. Duration: 01:05 Video provided by AFP
Powered by NewsLook.com
Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
American Ebola Patients Released: What Cured Them?

American Ebola Patients Released: What Cured Them?

Newsy (Aug. 21, 2014) It's unclear whether the American Ebola patients' recoveries can be attributed to an experimental drug or early detection and good medical care. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins