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Study confirms that cannabis is beneficial for multiple sclerosis

Date:
December 4, 2009
Source:
BioMed Central
Summary:
Cannabis can reduce spasticity in multiple sclerosis patients. A systematic review found that five out six randomized controlled trials reported a reduction in spasticity and an improvement in mobility.

Cannabis can reduce spasticity in multiple sclerosis (MS) patients. A systematic review, published in the open access journal BMC Neurology, found that five out six randomized controlled trials reported a reduction in spasticity and an improvement in mobility.

Shaheen Lakhan and Marie Rowland from the Global Neuroscience Initiative Foundation, Los Angeles, USA, searched for trials evaluating the cannabis extracts delta9-tetrahydrocannabinol (THC) and cannabidiol (CBD). According to Lakhan, "We found evidence that combined THC and CBD extracts may provide therapeutic benefit for MS spasticity symptoms."

Spasticity, involuntary muscle tension or contraction, is a common symptom of MS. Many existing therapies for this symptom are ineffective, difficult to obtain, or associated with intolerable side effects. In this study, reported incidence of side effects from cannabis, such as intoxication, varied greatly depending on the amount of cannabis needed to effectively limit spasticity, but the researchers note that side effects were also seen in the placebo groups. They add, "Considering the distress and limitations spasticity brings to individuals with MS, it is important to carefully weigh the potential for side effects with the potential for symptom relief ."

Lakhan concludes, "The therapeutic potential of cannabinoids in MS is comprehensive and should be given considerable attention."


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Shaheen E Lakhan and Marie Rowland. Whole plant cannabis extracts in the treatment of spasticity in multiple sclerosis: a systematic review. BMC Neurology, (in press)

Cite This Page:

BioMed Central. "Study confirms that cannabis is beneficial for multiple sclerosis." ScienceDaily. ScienceDaily, 4 December 2009. <www.sciencedaily.com/releases/2009/12/091203222136.htm>.
BioMed Central. (2009, December 4). Study confirms that cannabis is beneficial for multiple sclerosis. ScienceDaily. Retrieved April 16, 2014 from www.sciencedaily.com/releases/2009/12/091203222136.htm
BioMed Central. "Study confirms that cannabis is beneficial for multiple sclerosis." ScienceDaily. www.sciencedaily.com/releases/2009/12/091203222136.htm (accessed April 16, 2014).

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