Featured Research

from universities, journals, and other organizations

Children who survive cancer more likely to suffer from heart disease

Date:
December 10, 2009
Source:
BMJ-British Medical Journal
Summary:
Children and adolescents who survive cancer have a significantly higher risk of developing heart disease as young adults, according to a new large study.

Children and adolescents who survive cancer have a significantly higher risk of developing heart disease as young adults, according to the largest study on this issue published on the British Medical Journal website.

The findings show that young adult survivors of childhood cancer are at risk for a variety of cardiovascular complications related to their cancer therapy, such as heart failure, heart attacks, inflammation of the heart and heart valve abnormalities -- as late as 30 years after therapy.

They also show that this risk is apparent at lower exposures to anthracyclines (drugs used in chemotherapy) and radiation therapy than previously thought.

Given these results, the authors, led by Professor Daniel Mulrooney from the University of Minnesota, are calling on health providers to be aware of the increased risks when caring for individuals who have survived childhood cancer.

The authors compared data from 14,358 five year cancer survivors taking part in the Childhood Cancer Survivor Study with 3,899 siblings of cancer survivors.

The cancer survivors were diagnosed between 1970 and 1986, before the age of 21. They had one of the following cancers: leukaemia, brain cancer, Hodgkin's lymphoma, non-Hodgkin's lymphoma, kidney cancer, neuroblastoma, soft tissue sarcoma, or bone cancer.

The participants or their parents completed questionnaires about their health, medical conditions, and surgical procedures since diagnosis.

Dr Mulrooney concludes that: "Young adults who survive childhood or adolescent cancer are clearly at risk for early cardiac morbidity and mortality not typically recognised within this age group. Such individuals require ongoing clinical monitoring, particularly as they approach ages in which cardiovascular disease becomes more prevalent."

In an accompanying editorial, two experts discuss what long term care should be offered to children who survive cancer.

UK guidelines recommend routine cardiac screening every five years, but many survivors currently receive no follow-up, they say. With the number of adult survivors steadily rising, they suggest a network of specialists that collaborate across age boundaries is needed to optimise the care pathways for patients with complex problems.


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Cite This Page:

BMJ-British Medical Journal. "Children who survive cancer more likely to suffer from heart disease." ScienceDaily. ScienceDaily, 10 December 2009. <www.sciencedaily.com/releases/2009/12/091208192003.htm>.
BMJ-British Medical Journal. (2009, December 10). Children who survive cancer more likely to suffer from heart disease. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2009/12/091208192003.htm
BMJ-British Medical Journal. "Children who survive cancer more likely to suffer from heart disease." ScienceDaily. www.sciencedaily.com/releases/2009/12/091208192003.htm (accessed October 1, 2014).

Share This



More Health & Medicine News

Wednesday, October 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Some Positive Ebola News: Outbreak 'Contained' In Nigeria

Some Positive Ebola News: Outbreak 'Contained' In Nigeria

Newsy (Sep. 30, 2014) The CDC says a new case of Ebola has not been reported in Nigeria for more than 21 days, leading to hopes the outbreak might be nearing its end. Video provided by Newsy
Powered by NewsLook.com
UN Ebola Mission Head: Immediate Action Is Crucial

UN Ebola Mission Head: Immediate Action Is Crucial

AFP (Sep. 30, 2014) The newly appointed head of the United Nations Mission for Ebola Emergency Response (UNMEER), Anthony Banbury, outlines operations to tackle the virus. Duration: 00:39 Video provided by AFP
Powered by NewsLook.com
CDC Confirms First Case of Ebola in US

CDC Confirms First Case of Ebola in US

AP (Sep. 30, 2014) The CDC has confirmed the first diagnosed case of Ebola in the United States. The patient is being treated at a Dallas hospital after traveling earlier this month from Liberia. (Sept. 30) Video provided by AP
Powered by NewsLook.com
New Breast Cancer Drug Extends Lives In Clinical Trial

New Breast Cancer Drug Extends Lives In Clinical Trial

Newsy (Sep. 30, 2014) In a clinical trial, breast cancer patients lived an average of 15 months longer when they received new drug Perjeta along with Herceptin. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins