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An alternative method of pancreatic biopsy

Date:
January 19, 2010
Source:
World Journal of Gastroenterology
Summary:
A research team from Taiwan assessed the safety, yield, and clinical utility of percutaneous transgastric computed tomography-guided biopsy in patients with pancreatic masses. They found that percutaneous transgastric biopsy of the pancreas in selected patients with a combination of a 17-gauge introducer needle and an 18-gauge biopsy gun can be safe and has a high successful rate.
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FULL STORY

A research team from Taiwan assessed the safety, yield, and clinical utility of percutaneous transgastric computed tomography-guided biopsy in patients with pancreatic masses. They found that percutaneous transgastric biopsy of the pancreas in selected patients with a combination of a 17-gauge introducer needle and an 18-gauge biopsy gun can be safe and has a high successful rate.

It is reasonable to obtain a histological diagnosis before treating patients who have pancreatic masses and are unsuitable or unwilling to undergo surgery. As the pancreas is a deep seated organ surrounded by other vital structures, it is a challenge for the physician to obtain an adequate specimen for histological examination. Endoscopic ultrasound-guided biopsy of pancreatic masses has been proved to be a safe and effective method. However, if the hospital has no such facilities or patients are unwilling or intolerant of the procedure, computed tomography (CT)-guided biopsy is an alternative method.

A research article to be published on December 21, 2009 in the World Journal of Gastroenterology addresses this question. A research team from Taiwan reviewed 34 CT-guided biopsies in patients with pancreas mass, of whom 24 (71%) had a direct path to the mass without passing through a major organ.

Their results showed tumor tissues were obtained in nine pancreatic biopsies, and histologic specimens for diagnosis were obtained in all cases. An immediate imaging study and clinical follow-up detected neither hemorrhage nor peritonitis. No delayed procedure-related complication was seen during the survival period of all patients.

They drew a conclusion that it is feasible to perform transgastric biopsy of a pancreatic lesion using a large needle.


Story Source:

The above story is based on materials provided by World Journal of Gastroenterology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Tseng HS, Chen CY, Chan WP, Chiang JH. Percutaneous transgastric computed tomography-guided biopsy of the pancreas using large needles. World Journal of Gastroenterology, 2009; 15 (47): 5972 DOI: 10.3748/wjg.15.5972

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World Journal of Gastroenterology. "An alternative method of pancreatic biopsy." ScienceDaily. ScienceDaily, 19 January 2010. <www.sciencedaily.com/releases/2010/01/100115093849.htm>.
World Journal of Gastroenterology. (2010, January 19). An alternative method of pancreatic biopsy. ScienceDaily. Retrieved May 22, 2015 from www.sciencedaily.com/releases/2010/01/100115093849.htm
World Journal of Gastroenterology. "An alternative method of pancreatic biopsy." ScienceDaily. www.sciencedaily.com/releases/2010/01/100115093849.htm (accessed May 22, 2015).

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