Featured Research

from universities, journals, and other organizations

New risk score tool more accurately predicts patients' risk for cardiac disease and death, study finds

Date:
March 15, 2010
Source:
Intermountain Medical Center
Summary:
By combining patients' Framingham Risk Score with new Intermountain Risk Score, researchers found that they were 30 percent more likely to correctly determine a woman's risk, and 57 percent more likely to determine a man's risk for a cardiovascular problem or death within 30 days of an angiography.

Researchers from the Heart Institute at Intermountain Medical Center in Murray, Utah, have devised a better way to determine an individual's risk for problems, such as heart attack and heart failure, according to a new study.

The research team has developed the Intermountain Risk Score, a measurement tool that looks at age and sex, but also adds the results of routine blood tests, which are not included in the assessment system commonly used by physicians today.

Researchers at Intermountain compared the Intermountain Risk Score with the Framingham Risk Score, currently the gold standard for measuring future coronary heart disease risk. The Framingham index looks at total cholesterol, HDL cholesterol, blood pressure, diabetes, age, and gender.

"Framingham does a good job of classifying groups of patients. But it's not as good at identifying an individual's risk for disease," says Benjamin Horne, PhD, director of cardiovascular and genetic epidemiology at the Heart Institute at Intermountain Medical Center, and the principal author of the study.

That's where the Intermountain Risk Score can help.

"Our research has shown that the Intermountain Risk Score really improves a doctor's ability to measure patient risk. And it does it by including two simple and inexpensive tests: the complete blood count and metabolic profiles," he says.

Results of the study from the Heart Institute at Intermountain Medical Center will be presented at 1:30 pm, EST, on March 14 at the American College of Cardiology's 59th annual scientific session in Atlanta.

Researchers followed over 5,000 patients who were treated for angiography, or vascular imaging. By combining the patients' Framingham Risk Score with their Intermountain Risk Score, researchers found that they were 30 percent more likely to correctly determine a woman's risk, and 57 percent more likely to determine a man's risk for a cardiovascular problem or death within 30 days of the angiography. The results remained substantially better than the Framingham score alone after one year (23 percent for women and 46 percent for men) and at five years (29 percent for women and 25 percent for men).

"Adding the Intermountain Risk Score to the Framingham Risk Score substantially improves our ability to determine an individual's risk of future coronary heart disease and associated problems," says Dr. Horne.

The Framingham Risk Score was developed as part of the Framingham Heart Study, which began in 1948 as a project of the National Heart, Lung and Blood Institute and Boston University. The objective of the study was to identify common characteristics that contribute to cardiovascular disease by following its development over a long period of time in a large group of participants who had not yet developed symptoms or suffered a heart attack or stroke.

Researchers at Intermountain Medical Center followed patients an average of three years after their angiogram, and some were followed for up to 10 years.

"We are in the process of replicating these findings at an academic center in North Carolina. Our previous studies of the Intermountain Risk Score showed that it applies very well both to patients and to the general population in different geographic settings, so we expect it will improve on the Framingham Risk Score in that East Coast population as well," Dr. Horne said. "We are also evaluating which health conditions are best predicted by the Intermountain Risk Score, and how changes over time in laboratory values influence the scoring system's ability to predict health outcomes."

Dr. Horne says that the goal at Intermountain Healthcare is to create an online risk score calculator to help clinicians around the world better assess their patients' health.


Story Source:

The above story is based on materials provided by Intermountain Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

Intermountain Medical Center. "New risk score tool more accurately predicts patients' risk for cardiac disease and death, study finds." ScienceDaily. ScienceDaily, 15 March 2010. <www.sciencedaily.com/releases/2010/03/100314150908.htm>.
Intermountain Medical Center. (2010, March 15). New risk score tool more accurately predicts patients' risk for cardiac disease and death, study finds. ScienceDaily. Retrieved July 28, 2014 from www.sciencedaily.com/releases/2010/03/100314150908.htm
Intermountain Medical Center. "New risk score tool more accurately predicts patients' risk for cardiac disease and death, study finds." ScienceDaily. www.sciencedaily.com/releases/2010/03/100314150908.htm (accessed July 28, 2014).

Share This




More Health & Medicine News

Monday, July 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Trees Could Save More Than 850 Lives Each Year

Trees Could Save More Than 850 Lives Each Year

Newsy (July 27, 2014) A national study conducted by the USDA Forest Service found that trees collectively save more than 850 lives on an annual basis. Video provided by Newsy
Powered by NewsLook.com
Google's Next Frontier: The Human Body

Google's Next Frontier: The Human Body

Newsy (July 27, 2014) Google is collecting genetic and molecular information to paint a picture of the perfectly healthy human. Video provided by Newsy
Powered by NewsLook.com
What's To Blame For Worst Ebola Outbreak In History?

What's To Blame For Worst Ebola Outbreak In History?

Newsy (July 27, 2014) A U.S. doctor has tested positive for the deadly Ebola virus, as the worst-ever outbreak continues to grow. Video provided by Newsy
Powered by NewsLook.com
Losing Sleep Leaves You Vulnerable To 'False Memories'

Losing Sleep Leaves You Vulnerable To 'False Memories'

Newsy (July 27, 2014) A new study shows sleep deprivation can make it harder for people to remember specific details of an event. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins