Featured Research

from universities, journals, and other organizations

Silver proves its mettle for nanotech applications

Date:
March 20, 2010
Source:
Arizona State University
Summary:
Scientists have introduced a new method to deterministically and precisely position silver nanoparticles onto self-assembling DNA scaffolds.

A long single-strand of DNA has been folded into a triangular building platform through a process known as DNA origami. This architectural foundation was then "decorated" with one, two or three silver nanoparticles, which self-assembled at pre-determined locations on the DNA nanostructure.
Credit: Hao Yan, Yan Liu, Biodesign Institute at Arizona State University

The self-assembling properties of the DNA molecule have allowed for the construction of an intriguing range of nanoscale forms. Such nanoarchitectures may eventually find their way into a new generation of microelectronics, semiconductors, biological and chemical sensing devices and a host of biomedical applications. Now Hao Yan and Yan Liu, professors at the Biodesign Institute's Center for Single Molecule Biophysics and their collaborators have introduced a new method to deterministically and precisely position silver nanoparticles onto self-assembling DNA scaffolds.

Related Articles


In their latest research, the group used a long single-strand of DNA, which had been folded into a triangular building platform through a process known as DNA origami. This architectural foundation was then 'decorated' with one, two or three silver nanoparticles, which self-assembled at pre-determined locations on the DNA nanostructure. The group's experimental results, which appear in the advanced online edition of the journal Angewandte Chemie, demonstrate for the first time the viability of using silver, rather than the gold nanoparticles traditionally applied to DNA-tile or origami based architectures. The study was co-authored by Suchetan Pal, Zhengtao Deng, Baoquan Ding.

One of many applications for DNA scaffolds studded with nanoparticles is to perform precise sensing operations at the molecular scale. Sensitive detection of single molecules with high specificity is of great scientific interest for chemists, biologists, pharmacologists, medical researchers and those involved in environmental areas where trace analysis is required. The detailed study of human genes is but one area where improved single-molecule detection could be of enormous benefit.

In their current effort, the group sought to exploit the properties of the silver nanoparticles to increase the surface plasmon resonance -- a vibration of electrons that can give researchers clues regarding the molecular nature of the sample they are studying. "Theoretically, people predicted that a local surface plasmon resonance can be much stronger if you use silver particles compared to gold," said Yan. These locally enhanced areas between nanoparticles are referred to as electrical hot spots.

The group however, had to overcome significant obstacles to the use of silver nanoparticles. Silver tends to be much less stable than gold and can easily oxidize in its normal state. To counter this tendency, Yan and Liu's team attached multiple sulfur atoms to the backbone of the DNA strand used to make the platform for the nanoparticles. Each silver nanoparticle is then firmly held in place by nine sulfur atoms, once it is mounted on the DNA origami shape.

The new study paves the way for creating a more functional DNA architecture. "I believe this work will open doors to implement and study distance-dependent plasmonic interaction between noble nanoparticles at the single particle level," Yan said, adding that the first critical steps to creating hierarchically organized silver nanoparticle structures have now been taken.


Story Source:

The above story is based on materials provided by Arizona State University. The original article was written by Richard Harth, Biodesign Institute Science Writer. Note: Materials may be edited for content and length.


Journal Reference:

  1. Suchetan Pal, Zhengtao Deng, Baoquan Ding, Hao Yan, Yan Liu. DNA-Origami-Directed Self-Assembly of Discrete Silver-Nanoparticle Architectures. Angewandte Chemie International Edition, 2010; DOI: 10.1002/anie.201000330

Cite This Page:

Arizona State University. "Silver proves its mettle for nanotech applications." ScienceDaily. ScienceDaily, 20 March 2010. <www.sciencedaily.com/releases/2010/03/100319115629.htm>.
Arizona State University. (2010, March 20). Silver proves its mettle for nanotech applications. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2010/03/100319115629.htm
Arizona State University. "Silver proves its mettle for nanotech applications." ScienceDaily. www.sciencedaily.com/releases/2010/03/100319115629.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Matter & Energy News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

NASA's First 3-D Printer In Space Creates Its First Object

NASA's First 3-D Printer In Space Creates Its First Object

Newsy (Nov. 26, 2014) The International Space Station is now using a proof-of-concept 3D printer to test additive printing in a weightless, isolated environment. Video provided by Newsy
Powered by NewsLook.com
Bolivian Recycling Initiative Turns Plastic Waste Into School Furniture

Bolivian Recycling Initiative Turns Plastic Waste Into School Furniture

Reuters - Innovations Video Online (Nov. 26, 2014) Innovative recycling project in La Paz separates city waste and converts plastic garbage into school furniture made from 'plastiwood'. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Who Will Failed Nuclear Talks Hurt Most?

Who Will Failed Nuclear Talks Hurt Most?

Reuters - Business Video Online (Nov. 25, 2014) With no immediate prospect of sanctions relief for Iran, and no solid progress in negotiations with the West over the country's nuclear programme, Ciara Lee asks why talks have still not produced results and what a resolution would mean for both parties. Video provided by Reuters
Powered by NewsLook.com
Flying Enthusiast Converts Real-Life Aircraft Cockpit Into Simulator

Flying Enthusiast Converts Real-Life Aircraft Cockpit Into Simulator

Reuters - Innovations Video Online (Nov. 25, 2014) A virtual flying enthusiast converts parts of a written-off Airbus aircraft into a working flight simulator in his northern Slovenian home. Jim Drury reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins