Featured Research

from universities, journals, and other organizations

Leukemia-related protein 16 and colorectal carcinoma

Date:
April 9, 2010
Source:
World Journal of Gastroenterology
Summary:
A research team from China investigated the expression of leukemia-related protein 16 (LRP16) in colorectal cancer and normal mucosas and possible relationship between LRP16 expression and clinicopathological variables. Their study showed that the expression of LRP16 is related to the degree of differentiation, invasiveness, metastasis and prognosis of colorectal carcinoma.

Leukemia related protein 16 (LRP16) gene is an important estrogen-responsive gene.

LRP16 gene plays an important role in the carcinogenesis and progression of hormone-dependent cancer. LRP16 expression was also reported to be associated with invasion, metastasis and prognosis of gastric carcinoma. But no comprehensive description of LRP16 protein expression in colorectal cancer has been reported.

A research article to be published on April 7, 2010 in the World Journal of Gastroenterology addresses this question. The research team led by Dr. Zhao from Department of Pathology, Chinese People's Liberation Army General Hospital, investigated the expression patterns of LRP16 protein in human colorectal cancers and compared the clinical and pathological variables including survival time of the patients.

Their results showed a significant association between high LRP16 expression in colorectal cancer and early disease progression or the disease related death. The researchers believe that the LRP16 expression status detected by immunohistochemistry may be a molecular marker to predict the prognosis of colorectal carcinoma patients.


Story Source:

The above story is based on materials provided by World Journal of Gastroenterology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Xi HQ, Zhao P, Han WD. Clinicopathological significance and prognostic value of LRP16 expression in colorectal carcinoma. World Journal of Gastroenterology, 2010; 16 (13): 1644 DOI: 10.3748/wjg.v16.i13.1644

Cite This Page:

World Journal of Gastroenterology. "Leukemia-related protein 16 and colorectal carcinoma." ScienceDaily. ScienceDaily, 9 April 2010. <www.sciencedaily.com/releases/2010/04/100409093215.htm>.
World Journal of Gastroenterology. (2010, April 9). Leukemia-related protein 16 and colorectal carcinoma. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2010/04/100409093215.htm
World Journal of Gastroenterology. "Leukemia-related protein 16 and colorectal carcinoma." ScienceDaily. www.sciencedaily.com/releases/2010/04/100409093215.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Xtreme Eating: Your Daily Caloric Intake All On One Plate

Xtreme Eating: Your Daily Caloric Intake All On One Plate

Newsy (July 30, 2014) The Center for Science in the Public Interest released its 2014 list of single meals with whopping calorie counts. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins