Featured Research

from universities, journals, and other organizations

Leukemia-related protein 16 and colorectal carcinoma

Date:
April 9, 2010
Source:
World Journal of Gastroenterology
Summary:
A research team from China investigated the expression of leukemia-related protein 16 (LRP16) in colorectal cancer and normal mucosas and possible relationship between LRP16 expression and clinicopathological variables. Their study showed that the expression of LRP16 is related to the degree of differentiation, invasiveness, metastasis and prognosis of colorectal carcinoma.

Leukemia related protein 16 (LRP16) gene is an important estrogen-responsive gene.

Related Articles


LRP16 gene plays an important role in the carcinogenesis and progression of hormone-dependent cancer. LRP16 expression was also reported to be associated with invasion, metastasis and prognosis of gastric carcinoma. But no comprehensive description of LRP16 protein expression in colorectal cancer has been reported.

A research article to be published on April 7, 2010 in the World Journal of Gastroenterology addresses this question. The research team led by Dr. Zhao from Department of Pathology, Chinese People's Liberation Army General Hospital, investigated the expression patterns of LRP16 protein in human colorectal cancers and compared the clinical and pathological variables including survival time of the patients.

Their results showed a significant association between high LRP16 expression in colorectal cancer and early disease progression or the disease related death. The researchers believe that the LRP16 expression status detected by immunohistochemistry may be a molecular marker to predict the prognosis of colorectal carcinoma patients.


Story Source:

The above story is based on materials provided by World Journal of Gastroenterology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Xi HQ, Zhao P, Han WD. Clinicopathological significance and prognostic value of LRP16 expression in colorectal carcinoma. World Journal of Gastroenterology, 2010; 16 (13): 1644 DOI: 10.3748/wjg.v16.i13.1644

Cite This Page:

World Journal of Gastroenterology. "Leukemia-related protein 16 and colorectal carcinoma." ScienceDaily. ScienceDaily, 9 April 2010. <www.sciencedaily.com/releases/2010/04/100409093215.htm>.
World Journal of Gastroenterology. (2010, April 9). Leukemia-related protein 16 and colorectal carcinoma. ScienceDaily. Retrieved January 25, 2015 from www.sciencedaily.com/releases/2010/04/100409093215.htm
World Journal of Gastroenterology. "Leukemia-related protein 16 and colorectal carcinoma." ScienceDaily. www.sciencedaily.com/releases/2010/04/100409093215.htm (accessed January 25, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, January 25, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Disneyland Measles Outbreak Spreads To 5 States

Disneyland Measles Outbreak Spreads To 5 States

Newsy (Jan. 24, 2015) Much of the Disneyland measles outbreak is being blamed on the anti-vaccination movement. The CDC encourages just about everyone get immunized. Video provided by Newsy
Powered by NewsLook.com
Growing Measles Outbreak Worries Calif. Parents

Growing Measles Outbreak Worries Calif. Parents

AP (Jan. 23, 2015) Public health officials are rushing to contain a measles outbreak that has sickened 70 people across 6 states and Mexico. The AP&apos;s Raquel Maria Dillon has more. (Jan. 23) Video provided by AP
Powered by NewsLook.com
Smart Wristband to Shock Away Bad Habits

Smart Wristband to Shock Away Bad Habits

Reuters - Innovations Video Online (Jan. 23, 2015) A Boston start-up is developing a wristband they say will help users break bad habits by jolting them with an electric shock. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
This Is What It's Like To Date A Med Student

This Is What It's Like To Date A Med Student

BuzzFeed (Jan. 23, 2015) Dating is now speed-dating... or studying. Video provided by BuzzFeed
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins