Featured Research

from universities, journals, and other organizations

Leukemia-related protein 16 and colorectal carcinoma

Date:
April 9, 2010
Source:
World Journal of Gastroenterology
Summary:
A research team from China investigated the expression of leukemia-related protein 16 (LRP16) in colorectal cancer and normal mucosas and possible relationship between LRP16 expression and clinicopathological variables. Their study showed that the expression of LRP16 is related to the degree of differentiation, invasiveness, metastasis and prognosis of colorectal carcinoma.

Leukemia related protein 16 (LRP16) gene is an important estrogen-responsive gene.

LRP16 gene plays an important role in the carcinogenesis and progression of hormone-dependent cancer. LRP16 expression was also reported to be associated with invasion, metastasis and prognosis of gastric carcinoma. But no comprehensive description of LRP16 protein expression in colorectal cancer has been reported.

A research article to be published on April 7, 2010 in the World Journal of Gastroenterology addresses this question. The research team led by Dr. Zhao from Department of Pathology, Chinese People's Liberation Army General Hospital, investigated the expression patterns of LRP16 protein in human colorectal cancers and compared the clinical and pathological variables including survival time of the patients.

Their results showed a significant association between high LRP16 expression in colorectal cancer and early disease progression or the disease related death. The researchers believe that the LRP16 expression status detected by immunohistochemistry may be a molecular marker to predict the prognosis of colorectal carcinoma patients.


Story Source:

The above story is based on materials provided by World Journal of Gastroenterology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Xi HQ, Zhao P, Han WD. Clinicopathological significance and prognostic value of LRP16 expression in colorectal carcinoma. World Journal of Gastroenterology, 2010; 16 (13): 1644 DOI: 10.3748/wjg.v16.i13.1644

Cite This Page:

World Journal of Gastroenterology. "Leukemia-related protein 16 and colorectal carcinoma." ScienceDaily. ScienceDaily, 9 April 2010. <www.sciencedaily.com/releases/2010/04/100409093215.htm>.
World Journal of Gastroenterology. (2010, April 9). Leukemia-related protein 16 and colorectal carcinoma. ScienceDaily. Retrieved August 29, 2014 from www.sciencedaily.com/releases/2010/04/100409093215.htm
World Journal of Gastroenterology. "Leukemia-related protein 16 and colorectal carcinoma." ScienceDaily. www.sciencedaily.com/releases/2010/04/100409093215.htm (accessed August 29, 2014).

Share This




More Health & Medicine News

Friday, August 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

3 Things To Know About The Ebola Outbreak's Progression

3 Things To Know About The Ebola Outbreak's Progression

Newsy (Aug. 29, 2014) Here are three things you need to know about the deadly Ebola outbreak's progression this week. Video provided by Newsy
Powered by NewsLook.com
Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com
Who Could Be Burnt by WHO's E-Cigs Move?

Who Could Be Burnt by WHO's E-Cigs Move?

Reuters - Business Video Online (Aug. 28, 2014) The World Health Organisation has called for the regulation of electronic cigarettes as both tobacco and medical products. Ciara Lee looks at the impact of the move on the tobacco industry. Video provided by Reuters
Powered by NewsLook.com
CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

Newsy (Aug. 28, 2014) CDC director Tom Frieden says the Ebola outbreak is even worse than he feared. But he also said there's still hope to contain it. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins