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New procedure aims to save vision of children with eye cancer

Date:
April 16, 2010
Source:
Washington University School of Medicine
Summary:
An ophthalmologist is implanting radioactive discs in the eyes of children with a rare cancer in an attempt to save their vision and eyes. The treatment for the rare childhood eye cancer, called retinoblastoma, involves implanting a small disc, or plaque, which stays in the eye for three days before a second surgery to remove it.
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An ophthalmologist at Washington University School of Medicine in St. Louis is implanting radioactive discs in the eyes of children with a rare cancer in an attempt to save their vision and their eyes.

J. William Harbour, MD, is one of only a few doctors nationwide to use the approach for treating a rare, childhood eye cancer, called retinoblastoma. Harbour, the Paul A. Cibis Distinguished Professor of Ophthalmology and Visual Sciences, performs the surgery at St. Louis Children's Hospital. He implants a small disc, or plaque, which stays in the eye for three days before a second surgery to remove it.

"The standard of care for retinoblastoma is chemotherapy, followed by laser and freezing treatments to eliminate the last remnants of tumors," Harbour says. "But occasionally there will be a tumor that doesn't respond to chemotherapy or is too large to treat with a laser or freezing treatment. That's where this plaque treatment comes in. It gives us an option that may allow us to save the eyes of a young child."

Retinoblastoma, as the name suggests, is characterized by tumors in the eye's retina. It is extremely rare, affecting about one child in 20,000. In the United States, about 200 children each year are diagnosed with retinoblastoma. Approximately 40 percent of them develop tumors in both eyes, so in cases where the tumors prove resistant to chemotherapy, very young children and their parents are faced with a choice between a life without eyes and a high risk of death.

That's why Harbour, also a professor of cell biology and of molecular oncology and director of ocular oncology at the Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine, and a handful of other eye cancer specialists have recently started using the plaque method to treat the cancer and possibly save the eyes.


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The above post is reprinted from materials provided by Washington University School of Medicine. The original item was written by Jim Dryden. Note: Materials may be edited for content and length.


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Washington University School of Medicine. "New procedure aims to save vision of children with eye cancer." ScienceDaily. ScienceDaily, 16 April 2010. <www.sciencedaily.com/releases/2010/04/100414122645.htm>.
Washington University School of Medicine. (2010, April 16). New procedure aims to save vision of children with eye cancer. ScienceDaily. Retrieved August 2, 2015 from www.sciencedaily.com/releases/2010/04/100414122645.htm
Washington University School of Medicine. "New procedure aims to save vision of children with eye cancer." ScienceDaily. www.sciencedaily.com/releases/2010/04/100414122645.htm (accessed August 2, 2015).

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