Featured Research

from universities, journals, and other organizations

Childhood body size affects future breast cancer chances, study finds

Date:
April 15, 2010
Source:
BioMed Central
Summary:
Thinner girls may be at higher risk of breast cancer. Researchers have found that girls who were leaner at age seven were at higher risk of cancer later in life.

Thinner girls may be at higher risk of breast cancer. Researchers writing in BioMed Central's open access journal Breast Cancer Research found that girls who were leaner at age seven were at higher risk of cancer later in life.

Related Articles


Jingmei Li worked with a team of researchers from the Karolinska Institutet, Sweden, to study the relationships between childhood body size and tumour characteristics in a group of 2,818 Swedish breast cancer patients and 3,111 controls. She said, "Our main finding was that a large body type at age seven years was associated with a decreased risk of postmenopausal breast cancer. Although strongly associated with other known risk factors such as age of menarche, adult BMI and breast density, size at age seven years remained a significant protective factor after adjustment for these other issues."

Size at age seven was also found to determine tumour characteristics, in particular, estrogen receptor status. A large body size at age seven was especially protective against estrogen receptor negative tumours, which generally fare worse in terms of prognosis. The researchers' classification of childhood body size was derived from nine numbered pictograms ranging from very skinny (S1) to very fat (S9). Subjects assessed their own body type at present and how they remembered themselves at seven years old. These selections were then used to group them as lean (S1 to S2), medium (S3 to S4) and large (S5 to S9). Li said, "It appears counterintuitive that a large body size during childhood can reduce breast cancer risk, because a large birth weight and a high adult BMI have been shown to otherwise elevate breast cancer risk. There remain unanswered questions on mechanisms driving this protective effect."

These findings may have important implications. The researchers conclude, "Given the strength of the associations, and the ease of retrieval of information on childhood shape from old photographs, childhood body size is potentially useful for building breast cancer risk or prognosis models."


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Jingmei Li, Keith Humphreys, Louise Eriksson, Kamila Czene, Jianjun Liu and Per Hall. Effects of childhood body size on breast cancer tumour characteristics. Breast Cancer Research, 2010; (in press) [link]

Cite This Page:

BioMed Central. "Childhood body size affects future breast cancer chances, study finds." ScienceDaily. ScienceDaily, 15 April 2010. <www.sciencedaily.com/releases/2010/04/100414193814.htm>.
BioMed Central. (2010, April 15). Childhood body size affects future breast cancer chances, study finds. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2010/04/100414193814.htm
BioMed Central. "Childhood body size affects future breast cancer chances, study finds." ScienceDaily. www.sciencedaily.com/releases/2010/04/100414193814.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Why Your Boss Should Let You Sleep In

Why Your Boss Should Let You Sleep In

Newsy (Dec. 17, 2014) According to research out of the University of Pennsylvania, waking up for work is the biggest factor that causes Americans to lose sleep. Video provided by Newsy
Powered by NewsLook.com
Flu Outbreak Closing Schools in Ohio

Flu Outbreak Closing Schools in Ohio

AP (Dec. 17, 2014) A wave of flu illnesses has forced some Ohio schools to shut down over the past week. State officials confirmed one pediatric flu-related death, a 15-year-old girl in southern Ohio. (Dec. 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins