Featured Research

from universities, journals, and other organizations

Childhood body size affects future breast cancer chances, study finds

Date:
April 15, 2010
Source:
BioMed Central
Summary:
Thinner girls may be at higher risk of breast cancer. Researchers have found that girls who were leaner at age seven were at higher risk of cancer later in life.

Thinner girls may be at higher risk of breast cancer. Researchers writing in BioMed Central's open access journal Breast Cancer Research found that girls who were leaner at age seven were at higher risk of cancer later in life.

Jingmei Li worked with a team of researchers from the Karolinska Institutet, Sweden, to study the relationships between childhood body size and tumour characteristics in a group of 2,818 Swedish breast cancer patients and 3,111 controls. She said, "Our main finding was that a large body type at age seven years was associated with a decreased risk of postmenopausal breast cancer. Although strongly associated with other known risk factors such as age of menarche, adult BMI and breast density, size at age seven years remained a significant protective factor after adjustment for these other issues."

Size at age seven was also found to determine tumour characteristics, in particular, estrogen receptor status. A large body size at age seven was especially protective against estrogen receptor negative tumours, which generally fare worse in terms of prognosis. The researchers' classification of childhood body size was derived from nine numbered pictograms ranging from very skinny (S1) to very fat (S9). Subjects assessed their own body type at present and how they remembered themselves at seven years old. These selections were then used to group them as lean (S1 to S2), medium (S3 to S4) and large (S5 to S9). Li said, "It appears counterintuitive that a large body size during childhood can reduce breast cancer risk, because a large birth weight and a high adult BMI have been shown to otherwise elevate breast cancer risk. There remain unanswered questions on mechanisms driving this protective effect."

These findings may have important implications. The researchers conclude, "Given the strength of the associations, and the ease of retrieval of information on childhood shape from old photographs, childhood body size is potentially useful for building breast cancer risk or prognosis models."


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Jingmei Li, Keith Humphreys, Louise Eriksson, Kamila Czene, Jianjun Liu and Per Hall. Effects of childhood body size on breast cancer tumour characteristics. Breast Cancer Research, 2010; (in press) [link]

Cite This Page:

BioMed Central. "Childhood body size affects future breast cancer chances, study finds." ScienceDaily. ScienceDaily, 15 April 2010. <www.sciencedaily.com/releases/2010/04/100414193814.htm>.
BioMed Central. (2010, April 15). Childhood body size affects future breast cancer chances, study finds. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2010/04/100414193814.htm
BioMed Central. "Childhood body size affects future breast cancer chances, study finds." ScienceDaily. www.sciencedaily.com/releases/2010/04/100414193814.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Vaccine Might Be Coming, But Where's It Been?

Ebola Vaccine Might Be Coming, But Where's It Been?

Newsy (Aug. 1, 2014) Health officials are working to fast-track a vaccine — the West-African Ebola outbreak has killed more than 700. But why didn't we already have one? Video provided by Newsy
Powered by NewsLook.com
Study Links Certain Birth Control Pills To Breast Cancer

Study Links Certain Birth Control Pills To Breast Cancer

Newsy (Aug. 1, 2014) Previous studies have made the link between birth control and breast cancer, but the latest makes the link to high-estrogen oral contraceptives. Video provided by Newsy
Powered by NewsLook.com
House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Uganda on Alert for Ebola but No Confirmed Cases

Uganda on Alert for Ebola but No Confirmed Cases

AFP (July 31, 2014) Uganda's health minister said on Thursday that there are no confirmed cases of Ebola in the country, but that it remained on alert for cases of the deadly virus. Uganda has suffered Ebola outbreaks in the past, most recently in 2012. Duration: 00:59 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins