Featured Research

from universities, journals, and other organizations

Framingham risk assessment doesn't accurately predict coronary artery disease, study suggests

Date:
April 21, 2010
Source:
American College of Radiology / American Roentgen Ray Society
Summary:
If patients with suspected coronary artery disease are excluded from further screening because of a low Framingham score, many patients with substantial atherosclerosis (a build-up of plaque inside the arteries) will be missed, according to a new study.

If patients with suspected coronary artery disease (CAD) are excluded from further screening because of a low Framingham score, many patients with substantial atherosclerosis (a build-up of plaque inside the arteries) will be missed, according to a study published in the May issue of the American Journal of Roentgenology.

Related Articles


The Framingham risk assessment tool is used to estimate a person's chances of having a heart attack based upon age, sex, total cholesterol, HDL cholesterol, smoking status, and blood pressure. "It is often recommended as the starting point for coronary disease screening; however, if a patient's Framingham score is low enough, some doctors may eliminate them from having any further screening," said Kevin M. Johnson, MD, lead author of the study.

The study, performed at the Yale University School of Medicine in New Haven, CT, compared the sensitivity (percentage of patients with atherosclerosis who were correctly identified) of the Framingham score to the simple observation of whether any coronary calcium was present using coronary computed tomography (CT). It included 1,416 men and 707 women with suspected CAD and the majority of patients were asymptomatic

"Simple observation of the presence of coronary calcium was 98 percent sensitive in men and 97 percent sensitive in women for the detection of atherosclerosis. In comparison, the Framingham risk score was only 74 percent sensitive in men and 36 percent sensitive in women for the detection of atherosclerosis -- a substantial difference," said Johnson.

"As our study suggests, the presence of coronary artery calcium detects more patients with coronary atherosclerosis than does the Framingham risk assessment score," he said.

"If the Framingham risk score is used as the "gatekeeper" in a screening program for coronary atherosclerosis and the low-risk patients are dismissed from further study, about two thirds of women and a quarter of men with substantial atherosclerosis will be missed," said Johnson.

This study appears in the May issue of the American Journal of Roentgenology.


Story Source:

The above story is based on materials provided by American College of Radiology / American Roentgen Ray Society. Note: Materials may be edited for content and length.


Cite This Page:

American College of Radiology / American Roentgen Ray Society. "Framingham risk assessment doesn't accurately predict coronary artery disease, study suggests." ScienceDaily. ScienceDaily, 21 April 2010. <www.sciencedaily.com/releases/2010/04/100421111351.htm>.
American College of Radiology / American Roentgen Ray Society. (2010, April 21). Framingham risk assessment doesn't accurately predict coronary artery disease, study suggests. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2010/04/100421111351.htm
American College of Radiology / American Roentgen Ray Society. "Framingham risk assessment doesn't accurately predict coronary artery disease, study suggests." ScienceDaily. www.sciencedaily.com/releases/2010/04/100421111351.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins