Featured Research

from universities, journals, and other organizations

Coronary CTA a cost-effective alternative to cardiac catheterization for the evaluation of CAD, study suggests

Date:
April 21, 2010
Source:
Thomas Jefferson University
Summary:
Noninvasive coronary computed tomography angiography (CTA) is a cost-effective alternative to invasive cardiac catheterization in the care of patients who have positive stress test results but a less than 50 percent chance of actually having significant coronary artery disease (CAD) according to a new study.

According to a study conducted at Thomas Jefferson University (TJU), non-invasive coronary computed tomography angiography (CTA) is a cost-effective alternative to invasive cardiac catheterization in the care of patients who have positive stress test results but a less than 50 percent chance of actually having significant coronary artery disease (CAD).

The study will be published in the May issue of the American Journal of Roentgenology. CAD is a narrowing of the blood vessels that supply blood and oxygen to the heart. If left untreated, it can lead to a heart attack.

"Patients with positive stress test results but no heart-related symptoms, as well as patients with a positive stress test with atypical chest pain often receive referrals for cardiac catheterization for the evaluation of CAD," said the study's lead author, Ethan J. Halpern, M.D., professor, Department of Radiology at Jefferson Medical College, and director, Cardiac CT at Thomas Jefferson University Hospital. "Coronary CTA is an alternative, non-invasive diagnostic imaging test that can be used to effectively triage these patients."

The study compared the false-negative rates, false-positive rates, costs, and radiation exposure of direct referral of patients for cardiac catheterization with the values associated with performing coronary CTA before catheterization.

"At a 50 percent prevalence of CAD, we found that performing coronary CTA before cardiac catheterization results in an average cost saving of $789 per patient with a false-negative rate of 2.5 percent and average additional radiation exposure of 1-2 mSv, which is minimal," said Dr. Halpern.

According to the study results, when a patient with an expected CAD prevalence less than 85 percent is found to have a positive stress test result, coronary CTA is a less expensive alternative to direct performance of cardiac catheterization. Recent studies have demonstrated that diagnostic cardiac catheterization of patients with atypical symptoms will demonstrate significant CAD less than half of the time. If the pretest probability of CAD is low, the coronary CTA findings are more likely to obviate cardiac catheterization and thereby reduce both the cost and effective radiation dose of the workup.

The study's co-authors also from Jefferson are: David C. Levin, M.D., professor, Department of Radiology; and Michael Savage, M.D., associate professor, and David Fischman, M.D., associate professor, both of the Division of Cardiology in the Department of Medicine.


Story Source:

The above story is based on materials provided by Thomas Jefferson University. Note: Materials may be edited for content and length.


Cite This Page:

Thomas Jefferson University. "Coronary CTA a cost-effective alternative to cardiac catheterization for the evaluation of CAD, study suggests." ScienceDaily. ScienceDaily, 21 April 2010. <www.sciencedaily.com/releases/2010/04/100421162617.htm>.
Thomas Jefferson University. (2010, April 21). Coronary CTA a cost-effective alternative to cardiac catheterization for the evaluation of CAD, study suggests. ScienceDaily. Retrieved September 20, 2014 from www.sciencedaily.com/releases/2010/04/100421162617.htm
Thomas Jefferson University. "Coronary CTA a cost-effective alternative to cardiac catheterization for the evaluation of CAD, study suggests." ScienceDaily. www.sciencedaily.com/releases/2010/04/100421162617.htm (accessed September 20, 2014).

Share This



More Health & Medicine News

Saturday, September 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins