Featured Research

from universities, journals, and other organizations

Genealogy may affect clinical differences in systemic lupus erythmatosus patients

Date:
June 18, 2010
Source:
European League Against Rheumatism
Summary:
The effects of systemic lupus erythematosus (SLE) may differ based on the individual patient's genealogical heritage, according to results of a new study. In particular, the study reinforced differences in SLE phenotype found between Northern and Southern European subpopulations.

The effects of Systemic Lupus Erythematosus (SLE) may differ based on the individual patient's genealogical heritage, according to results of a new study presented June 18 at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy. In particular, the study reinforced differences in SLE phenotype found between Northern and Southern European subpopulations.

Related Articles


Results from a Europe-wide study, involving 1,555 SLE patients from nine European countries, showed that photosensitivity was 9.4% more prevalent among patients from the Northern group (p=0.00056) versus the Southern group, while arthritis was 10.7% more prevalent in patients from the Southern group (p=0.0000017) versus the Northern group. These findings replicated results from previous studies.

"SLE affects 40 people in every 100,000 in Europe , so our study helps us further understand the impact of this complex disease on patients," said Professor Antonio Gonzalez, Rheumatology Unit, Hospital Clinico Universitario, Santiago de Compostela, Spain, and lead author of the study. Our research reinforces results from previous studies that prove there is evidence of genetic differences between SLE patients from Northern or Southern Europe. Therefore, results from studies in European SLE patients should acknowledge genealogy when reporting clinical differences between patients prior to providing their conclusions."

The study compared 475 SLE patients from Northern Europe (Germany, Hungary, The Czech Republic, The Netherlands, and Slovakia) with 1,080 SLE patients from Southern Europe (Greece, Italy, Portugal, and Spain). Investigators analysed the prevalence of the following clinical features between the recruiting centres in the Northern and in the Southern subgroups: serositis, immunologic disorder, malar rash, photosensitivity, arthritis, haematologic disorder, antinuclear antibodies and mean age of disease onset.


Story Source:

The above story is based on materials provided by European League Against Rheumatism. Note: Materials may be edited for content and length.


Cite This Page:

European League Against Rheumatism. "Genealogy may affect clinical differences in systemic lupus erythmatosus patients." ScienceDaily. ScienceDaily, 18 June 2010. <www.sciencedaily.com/releases/2010/06/100618081327.htm>.
European League Against Rheumatism. (2010, June 18). Genealogy may affect clinical differences in systemic lupus erythmatosus patients. ScienceDaily. Retrieved October 30, 2014 from www.sciencedaily.com/releases/2010/06/100618081327.htm
European League Against Rheumatism. "Genealogy may affect clinical differences in systemic lupus erythmatosus patients." ScienceDaily. www.sciencedaily.com/releases/2010/06/100618081327.htm (accessed October 30, 2014).

Share This



More Health & Medicine News

Thursday, October 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Fauci Says Ebola Risk in US "essentially Zero"

Fauci Says Ebola Risk in US "essentially Zero"

AP (Oct. 30, 2014) NIAID Director Anthony Fauci said the risk of Ebola becoming an epidemic in the U.S. is essentially zero Thursday at the Washington Ideas Forum. He also said an Ebola vaccine will be tested in West Africa in the next few months. (Oct. 30) Video provided by AP
Powered by NewsLook.com
Nurse Defies Ebola Quarantine With Bike Ride

Nurse Defies Ebola Quarantine With Bike Ride

AP (Oct. 30, 2014) A nurse who vowed to defy Maine's voluntary quarantine for health care workers who treated Ebola patients followed through on her promise Thursday, leaving her home for an hour-long bike ride. (Oct. 30) Video provided by AP
Powered by NewsLook.com
Pot-Infused Edibles Raise Concerns in Colorado

Pot-Infused Edibles Raise Concerns in Colorado

AFP (Oct. 30, 2014) Colorado may have legalized marijuana for recreational use, but the debate around the decision still continues, with a recent - failed - attempt to ban cannabis-infused edibles. Duration: 01:53 Video provided by AFP
Powered by NewsLook.com
British Navy Ship Arrives in Sierra Leone With Ebola Aid

British Navy Ship Arrives in Sierra Leone With Ebola Aid

AFP (Oct. 30, 2014) The British ship RFA ARGUS arrived in Sierra Leone to deliver supplies and equipment to help the fight against Ebola. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins