Featured Research

from universities, journals, and other organizations

Women with polycystic ovary syndrome have higher BPA blood levels, study finds

Date:
June 25, 2010
Source:
The Endocrine Society
Summary:
Women with the polycystic ovary syndrome (PCOS), the most common hormone imbalance in women of reproductive age, may be more vulnerable to exposure to the chemical bisphenol A (BPA), found in many plastic household items, according to a new study.

Women with the polycystic ovary syndrome (PCOS), the most common hormone imbalance in women of reproductive age, may be more vulnerable to exposure to the chemical bisphenol A (BPA), found in many plastic household items, according to a new study. The results are being presented at The Endocrine Society's 92nd Annual Meeting in San Diego.

The study found that BPA, a known hormone disrupter, is elevated and associated with higher levels of male hormones in the blood of women with PCOS compared with healthy women. These findings held true for both lean and obese women with PCOS, said Evanthia Diamanti-Kandarakis, MD, PhD, study co-author and professor at the University of Athens Medical School in Greece.

"Women with the polycystic ovary syndrome should be alert regarding this environmental contaminant's potential adverse effects on reproductive aspects of their health problem," she said.

Excessive secretion of androgens -- masculinization-promoting hormones -- occurs in PCOS. The syndrome raises the risk of infertility, obesity, Type 2 diabetes and heart disease.

Past studies show that BPA is elevated in women who have had recurrent miscarriages. This chemical can leach into the bloodstream from food and beverage containers that are made of polycarbonate hard plastic or lined with epoxy resins, or from some dental sealants and composites.

In the new study, the researchers divided 71 women with PCOS and 100 healthy female control subjects into subgroups matched by age and body composition (obese or lean). Blood levels of BPA, compared with those of controls, were nearly 60 percent higher in lean women with PCOS and more than 30 percent higher in obese women with the syndrome.

Additionally, as the BPA blood level increased, so did the concentrations of the male sex hormone testosterone and androstenedione, a steroid hormone that converts to testosterone, Diamanti-Kandarakis reported.

Although BPA is a weak estrogen, excessive secretion of androgens, as seen in PCOS, interfere with BPA detoxification by the liver, leading to accumulation of blood levels of BPA, Diamanti-Kandarakis explained.

"BPA also affects androgen metabolism, creating a vicious circle between androgens and BPA," she said.

Diamanti-Kandarakis said women with PCOS may want to limit their exposure to BPA.

"However," she said, "no one has proved that by reducing BPA levels in PCOS, it will have beneficial effects."


Story Source:

The above story is based on materials provided by The Endocrine Society. Note: Materials may be edited for content and length.


Cite This Page:

The Endocrine Society. "Women with polycystic ovary syndrome have higher BPA blood levels, study finds." ScienceDaily. ScienceDaily, 25 June 2010. <www.sciencedaily.com/releases/2010/06/100621143602.htm>.
The Endocrine Society. (2010, June 25). Women with polycystic ovary syndrome have higher BPA blood levels, study finds. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2010/06/100621143602.htm
The Endocrine Society. "Women with polycystic ovary syndrome have higher BPA blood levels, study finds." ScienceDaily. www.sciencedaily.com/releases/2010/06/100621143602.htm (accessed April 18, 2014).

Share This



More Health & Medicine News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins