Featured Research

from universities, journals, and other organizations

HPV vaccine gives prolonged protection against genital warts and low-grade pre-cancerous growths

Date:
July 21, 2010
Source:
BMJ-British Medical Journal
Summary:
Vaccination against certain types of human papillomavirus gives strong and sustained protection against genital warts and pre-cancerous growths of the cervix, according to a new study.

Vaccination against certain types of human papillomavirus (HPV) gives strong and sustained protection against genital warts and pre-cancerous growths of the cervix, according to a new study published online in the British Medical Journal.

Related Articles


An international study found that the quadrivalent HPV vaccine is helpful in preventing warts and low grade lesions related to HPV (types 6, 11, 16 and 18).

HPVs are responsible for around 500,000 cases of cervical cancer a year globally and 10 million further cases of high grade cervical intraepithelial neoplasia, which are immediate precusors to malignant cancerous growths.

In addition, it is estimated that 30 million women and men acquire anogenital warts (known as condyloma acuminata) or low-grade cervical growths each year.

The vaccine for HPV types 6, 11, 16 and 18 has the potential to prevent about 70% of cervical cancers and 90% of genital warts, but what contribution the vaccines make to low grade growths is still uncertain.

So an international group of investigators set out to find how useful the vaccines were in preventing low grade disease.

They studied results from 17,622 women aged 16-26 enrolled into two studies between December 2001 and May 2003. The women were enrolled from primary care centres and university or hospital associated health centres in 24 countries and territories around the world.

The women were split at random into two groups -- one group was given three doses of HPV vaccine (for types 6, 11, 16 and 18) at day 1, month 2, and month 6 of the study, while the other women were given a placebo.

Results showed that amongst previously unexposed women who had received the vaccine, it was highly effective (96-100%) for preventing low grade lesions attributable to HPV types 6, 11, 16 and 18 for up to four years.

It also had considerable effectiveness against any lesion (regardless of HPV type), with a reduction of 30% of cervical low-grade growths, 48% of vulvar and 75% of vaginal low-grade growths. Genital warts were reduced by 83%.

The authors say the prolonged effectiveness of the vaccine in preventing low grade lesions is important and conclude: "These lesions occur shortly after infection and a reduction in these lesions will be the earliest clinically noticeable health gain to be realised by HPV vaccination.

"Low-grade cervical and vulvovaginal lesions are important from a public health perspective, as the diagnosis, follow-up, and treatment of these common lesions are associated with substantial patient anxiety, morbidity, and healthcare costs."


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. The FUTURE I/II Study Group. Four year efficacy of prophylactic human papillomavirus quadrivalent vaccine against low grade cervical, vulvar, and vaginal intraepithelial neoplasia and anogenital warts: randomised controlled trial. BMJ, 2010; 341: c3493 DOI: 10.1136/bmj.c3493

Cite This Page:

BMJ-British Medical Journal. "HPV vaccine gives prolonged protection against genital warts and low-grade pre-cancerous growths." ScienceDaily. ScienceDaily, 21 July 2010. <www.sciencedaily.com/releases/2010/07/100720212927.htm>.
BMJ-British Medical Journal. (2010, July 21). HPV vaccine gives prolonged protection against genital warts and low-grade pre-cancerous growths. ScienceDaily. Retrieved February 28, 2015 from www.sciencedaily.com/releases/2010/07/100720212927.htm
BMJ-British Medical Journal. "HPV vaccine gives prolonged protection against genital warts and low-grade pre-cancerous growths." ScienceDaily. www.sciencedaily.com/releases/2010/07/100720212927.htm (accessed February 28, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, February 28, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Reuters - Innovations Video Online (Feb. 27, 2015) A dongle that plugs into a Smartphone mimics a lab-based blood test for HIV and syphilis and can detect the diseases in 15 minutes, say researchers. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Doctor Says Head Transplants Possible Within Two Years

Doctor Says Head Transplants Possible Within Two Years

Buzz60 (Feb. 27, 2015) An Italian doctor is saying he could stick someone&apos;s head onto someone else&apos;s body. Patrick Jones (@Patrick_E_Jones) reports. Video provided by Buzz60
Powered by NewsLook.com
How Your Dentist Could Help Screen You For Diabetes

How Your Dentist Could Help Screen You For Diabetes

Newsy (Feb. 27, 2015) A new study from researchers at New York University suggests dentists could soon use blood samples taken from patients&apos; mouths to test for diabetes. Video provided by Newsy
Powered by NewsLook.com
The Best Tips to Makeover Your Health

The Best Tips to Makeover Your Health

Buzz60 (Feb. 27, 2015) If you&apos;re looking to boost your health this season, there are a few quick and easy steps to prompt you for success. Krystin Goodwin (@Krystingoodwin) has the best tips to give your health a makeover this spring! Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins