Featured Research

from universities, journals, and other organizations

Insulin resistance, type 2 diabetes may be linked to plaques associated with Alzheimer's disease, study suggests

Date:
August 26, 2010
Source:
American Academy of Neurology
Summary:
People with insulin resistance and type 2 diabetes appear to be at an increased risk of developing plaques in the brain that are associated with Alzheimer's disease, according to new research.

People with insulin resistance and type 2 diabetes appear to be at an increased risk of developing plaques in the brain that are associated with Alzheimer's disease, according to new research published in the August 25, 2010, issue of Neurology, the medical journal of the American Academy of Neurology.

Insulin resistance, or the stage before diabetes, happens when insulin, a hormone in the body, becomes less effective in lowering blood sugar.

"Type 2 diabetes and Alzheimer's disease are two epidemics growing at alarming levels around the world," said study author Kensuke Sasaki, MD, PhD, with Kyushu University in Fukuoka, Japan. "With the rising obesity rates and the fact that obesity is related to the rise in type 2 diabetes, these results are very concerning."

The study involved 135 people with an average age of 67 from Hisayama, Japan. The participants had several diabetes glucose tests to measure blood sugar levels. They were also monitored for symptoms of Alzheimer's disease over the next 10 to 15 years. During that time, about 16 percent developed Alzheimer's disease.

After the participants died, researchers examined their autopsied brains for the physical signs of Alzheimer's disease, called plaques and tangles. While 16 percent had symptoms of Alzheimer's disease while alive, a total of 65 percent had plaques.

The study found that people who had abnormal results on three tests of blood sugar control had an increased risk of developing plaques. Plaques were found in 72 percent of people with insulin resistance and 62 percent of people with no indication of insulin resistance. However, the study did not find a link between diabetes factors and tangles in the brain.

"Further studies are needed to determine if insulin resistance is a cause of the development of these plaques," said Sasaki. "It's possible that by controlling or preventing diabetes, we might also be helping to prevent Alzheimer's disease."


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Journal Reference:

  1. T. Matsuzaki, K. Sasaki, Y. Tanizaki, J. Hata, K. Fujimi, Y. Matsui, A. Sekita, S. O. Suzuki, S. Kanba, Y. Kiyohara, and T. Iwaki. Insulin resistance is associated with the pathology of Alzheimer disease. The Hisayama Study. Neurology, 2010; DOI: 10.1212/WNL.0b013e3181eee25f

Cite This Page:

American Academy of Neurology. "Insulin resistance, type 2 diabetes may be linked to plaques associated with Alzheimer's disease, study suggests." ScienceDaily. ScienceDaily, 26 August 2010. <www.sciencedaily.com/releases/2010/08/100825174104.htm>.
American Academy of Neurology. (2010, August 26). Insulin resistance, type 2 diabetes may be linked to plaques associated with Alzheimer's disease, study suggests. ScienceDaily. Retrieved April 20, 2014 from www.sciencedaily.com/releases/2010/08/100825174104.htm
American Academy of Neurology. "Insulin resistance, type 2 diabetes may be linked to plaques associated with Alzheimer's disease, study suggests." ScienceDaily. www.sciencedaily.com/releases/2010/08/100825174104.htm (accessed April 20, 2014).

Share This



More Health & Medicine News

Sunday, April 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins