Featured Research

from universities, journals, and other organizations

Is infertility more common in women with epilepsy?

Date:
October 12, 2010
Source:
American Academy of Neurology
Summary:
Women with epilepsy may be more likely to experience infertility, according to new research. The study of women in India found that women with epilepsy experienced infertility at more than twice the rate of that found in the general population. The research also found that women who were taking multiple epilepsy drugs were more likely to be infertile than those taking fewer drugs or no drugs for epilepsy.

Women with epilepsy may be more likely to experience infertility, according to new research published in the Oct. 12, 2010, print issue of Neurology®, the medical journal of the American Academy of Neurology.

The study of women in India found that women with epilepsy experienced infertility at more than twice the rate of that found in the general population. The research also found that women who were taking multiple epilepsy drugs were more likely to be infertile than those taking fewer drugs or no drugs for epilepsy.

The study involved 375 women with an average age of 26 who were anticipating becoming pregnant. The women were followed until they became pregnant or for up to 10 years. During that time, 62 percent became pregnant, while 38 percent remained infertile. The infertility rate for the women in the general population in India is 15 percent.

Those who were taking three or more drugs for epilepsy were 18 times more likely to be infertile than those taking no epilepsy drugs. Seven percent of those taking no epilepsy drugs were infertile, compared to 32 percent of those taking one epilepsy drug, 41 percent of those taking two epilepsy drugs, and 60 percent of those taking three or more epilepsy drugs.

"This may be due to the adverse effects of taking multiple drugs or it could be a more indirect effect because people who are taking multiple drugs are more likely to have severe epilepsy that is difficult to treat," said study author Sanjeev Thomas, DM, of the Sree Chitra Tirunal Institute for Medical Sciences and Technology in Trivandrum, India.

Older women and women with less than 10 years of education were also more likely to experience infertility. Thomas said the relationship between lower education and infertility could also be due to difficult-to-treat epilepsy, which may make completing additional years of education challenging.

The study found that most pregnancies occurred within two years. "Based on these findings, women with epilepsy should be counseled about the potential risk of infertility and referred for an evaluation if they have not conceived within two years," said editorial author Alison M. Pack, MD, of Columbia University in New York.

Those taking the drug phenobarbital had significant risk of infertility, but no such trend was observed with valproate or other drugs.

The study was supported by the Indian Council of Medical Research.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Sukumaran, Sapna Cheravalloor, Sarma, P. Sankara, Thomas, Sanjeev V. Polytherapy increases the risk of infertility in women with epilepsy. Neurology, 2010; 75: 1351-1355 [link]

Cite This Page:

American Academy of Neurology. "Is infertility more common in women with epilepsy?." ScienceDaily. ScienceDaily, 12 October 2010. <www.sciencedaily.com/releases/2010/10/101011173243.htm>.
American Academy of Neurology. (2010, October 12). Is infertility more common in women with epilepsy?. ScienceDaily. Retrieved July 30, 2014 from www.sciencedaily.com/releases/2010/10/101011173243.htm
American Academy of Neurology. "Is infertility more common in women with epilepsy?." ScienceDaily. www.sciencedaily.com/releases/2010/10/101011173243.htm (accessed July 30, 2014).

Share This




More Health & Medicine News

Wednesday, July 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) — Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) — Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) — At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Xtreme Eating: Your Daily Caloric Intake All On One Plate

Xtreme Eating: Your Daily Caloric Intake All On One Plate

Newsy (July 30, 2014) — The Center for Science in the Public Interest released its 2014 list of single meals with whopping calorie counts. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:  

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile iPhone Android Web
      Follow Facebook Twitter Google+
      Subscribe RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins