Featured Research

from universities, journals, and other organizations

Improved antibiotic coatings: Research aims to make medical devices safer by preventing biofilms

Date:
October 20, 2010
Source:
American Institute of Physics
Summary:
A research group in Australia is working on techniques to permanently bind antibacterial coatings to medical devices by binding them to a polymer layer.

Bacteria have a natural ability to attach themselves to surfaces, both natural and synthetic. Once attached, they often work cooperatively to form biofilms, thin layers of bacterial colonies that can coat the surface of a medical device and introduce the risk of infection. As a result, orthopedic implants, catheters, and even contact lenses can become vehicles for infection.

Related Articles


Antibacterial materials on the surface can reduce the risk but generally these materials do not stick well to the devices. A research group at the University of South Australia is working on techniques to permanently bind antibacterial coatings to medical devices by binding them to a polymer layer. They present their research at the AVS 57th International Symposium & Exhibition, which takes place this week at the Albuquerque Convention Center in New Mexico.

The Australian scientists start by applying a plasma polymer coating, a technique that works on many different base materials including glass, metal, and many polymers used in devices. This ultrathin film acts as a scaffold on which to bind materials that either signal the bacteria not to attach by interfering with the cell's attachment mechanism or that prevent multiplication once the bacteria are attached.

The presentation will compare several different antibiotics applied to the polymer film, including established antibiotic compounds, silver nanoparticles, and novel diterpene compounds derived from Australian plants that have been used in traditional medicine. Each approach has pros and cons that must be carefully weighed before using them on a device implanted in the human body.

"We believe that no solution will be universal so we want to establish an array of approaches," says Hans Griesser of the University of South Australia. "The new diterpene compounds that we are testing are structurally quite different from established antibacterial compounds, and they are effective against methicillin-resistant Staphylococcus aureus. That is what got us excited about them."


Story Source:

The above story is based on materials provided by American Institute of Physics. Note: Materials may be edited for content and length.


Cite This Page:

American Institute of Physics. "Improved antibiotic coatings: Research aims to make medical devices safer by preventing biofilms." ScienceDaily. ScienceDaily, 20 October 2010. <www.sciencedaily.com/releases/2010/10/101019171657.htm>.
American Institute of Physics. (2010, October 20). Improved antibiotic coatings: Research aims to make medical devices safer by preventing biofilms. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2010/10/101019171657.htm
American Institute of Physics. "Improved antibiotic coatings: Research aims to make medical devices safer by preventing biofilms." ScienceDaily. www.sciencedaily.com/releases/2010/10/101019171657.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Reuters - Innovations Video Online (Dec. 21, 2014) A team of scientists led by Danish chemist Jorn Christensen says they have isolated two chemical compounds within an existing antipsychotic medication that could be used to help a range of failing antibiotics work against killer bacterial infections, such as Tuberculosis. Jim Drury went to meet him. Video provided by Reuters
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Monarch Butterflies Descend Upon Mexican Forest During Annual Migration

Monarch Butterflies Descend Upon Mexican Forest During Annual Migration

Reuters - Light News Video Online (Dec. 19, 2014) Millions of monarch butterflies begin to descend onto Mexico as part of their annual migration south. Rough Cut (no reporter narration) Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins