Featured Research

from universities, journals, and other organizations

Canola-type rapeseed oil reduces the level of fibrinogen, a cause of thrombosis and inflammation, study finds

Date:
November 8, 2010
Source:
University of Helsinki
Summary:
According to new research on fatty acids, the consumption of canola-type rapeseed oil decreases the level of fibrinogen detrimental to health in the body. The increased fibrinogen level, caused by an imbalance in essential fats in one's diet, decreases when saturated fatty acids are replaced with rapeseed oil.

According to research on fatty acids conducted at the universities of Helsinki and Tampere, the consumption of canola-type rapeseed oil decreases the level of fibrinogen detrimental to health in the body. The increased fibrinogen level, caused by an imbalance in essential fats in one's diet, decreases when saturated fatty acids are replaced with rapeseed oil.

Related Articles


The research results were published in the journal Prostaglandins, Leukotrienes and Essential Fatty Acids.

A complex state of balance, the haemostatic balance, prevails in the bloodstream. One player in this balancing act is fibrinogen, the single most important blood coagulation factor. A high level of fibrinogen promotes the creation of thrombosis and maintains inflammation within the body. An increase in the fibrinogen level is closely linked with, for example, cardiovascular disease, strokes, diabetes, Alzheimer's disease and dementia.

The new research demonstrates for the first time that an increase in the fibrinogen level of the blood is largely caused by the lack of omega-3-alpha-linolenic acid in the diet. When there is too little of this beneficial fatty acid found in one's diet, an imbalance between fatty acids in the body is created. When the omega-3-alpha-linolenic acid level is too low, the body starts to manufacture more harmful omega-6-arachidonic acid out of the omega-6-linoleic acid, creating hormone-like compounds that cause thrombosis and inflammation. According to the researchers, the fat composition of rapeseed oil is optimal with regard to fatty acids essential to the body and consequently is well-suited to reduce the fibrinogen levels in the blood.

Levels of fibrinogen and cholesterol reduced

In all 42 research subjects, many of whom with high levels of fibrinogen and cholesterol, participated in the research. The study subjects replaced one-fourth of the food fat (margarine, cheese, butter) they used to rapeseed oil. The oil used was canola-quality spring turnip rape oil. They took about a tablespoon of oil a day, for example, mixed with a salad. The rapeseed oil dose doubled the intake of omega-3-alpha-linolenic acid during the experiment period of six weeks. Due to the regime, all higher-than-average fibrinogen levels decreased by approximately 30 per cent.

The research shows that controlling fibrinogen and cholesterol by changing the fat consumed is a point of departure in the prevention of diseases as well as from the perspective of successful individual medical treatment. According to Into Laakso, Ph.D. from the Faculty of Pharmacy at the University of Helsinki, harmful effects of fats in, for example, elderly people could be easily rectified by switching one-fourth of fats to rapeseed oil. Laakso also recommends that, in addition to cholesterol, healthcare centres should measure patients' fibrinogen levels.


Story Source:

The above story is based on materials provided by University of Helsinki. Note: Materials may be edited for content and length.


Journal Reference:

  1. T. Seppδnen-Laakso, I. Laakso, T. Lehtimδki, R. Rontu, E. Moilanen, T. Solakivi, L. Seppo, H. Vanhanen, K. Kiviranta, R. Hiltunen. Elevated plasma fibrinogen caused by inadequate α-linolenic acid intake can be reduced by replacing fat with canola-type rapeseed oil. Prostaglandins, Leukotrienes and Essential Fatty Acids, 2010; 83 (1): 45 DOI: 10.1016/j.plefa.2010.02.001

Cite This Page:

University of Helsinki. "Canola-type rapeseed oil reduces the level of fibrinogen, a cause of thrombosis and inflammation, study finds." ScienceDaily. ScienceDaily, 8 November 2010. <www.sciencedaily.com/releases/2010/11/101108072258.htm>.
University of Helsinki. (2010, November 8). Canola-type rapeseed oil reduces the level of fibrinogen, a cause of thrombosis and inflammation, study finds. ScienceDaily. Retrieved April 25, 2015 from www.sciencedaily.com/releases/2010/11/101108072258.htm
University of Helsinki. "Canola-type rapeseed oil reduces the level of fibrinogen, a cause of thrombosis and inflammation, study finds." ScienceDaily. www.sciencedaily.com/releases/2010/11/101108072258.htm (accessed April 25, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, April 25, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

85 Killed in Niger by Meningitis Since Start of Year

85 Killed in Niger by Meningitis Since Start of Year

AFP (Apr. 24, 2015) — A meningitis outbreak in Niger has killed 85 people since the start of the year prompting authorities to close schools in the capital Niamey until Monday. Video provided by AFP
Powered by NewsLook.com
C-Section Births a Trend in Brazil

C-Section Births a Trend in Brazil

AFP (Apr. 24, 2015) — More than half of Brazil&apos;s babies are born via cesarean section, as mothers and doctors opt for a faster and less painful experience despite the health risks. Duration: 02:02 Video provided by AFP
Powered by NewsLook.com
Anti-Malaria Jab Hope

Anti-Malaria Jab Hope

Reuters - News Video Online (Apr. 24, 2015) — The world&apos;s first anti-malaria vaccine could get the go-ahead for use in Africa from October if approved by international regulators. Paul Chapman reports. Video provided by Reuters
Powered by NewsLook.com
3D Food Printing: The Meal of the Future?

3D Food Printing: The Meal of the Future?

AP (Apr. 23, 2015) — Developers of 3D food printing hope the culinary technology will revolutionize the way we cook and eat. (April 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins