Featured Research

from universities, journals, and other organizations

IV drug could be major advance in halting acute seizures in newborns

Date:
December 7, 2010
Source:
American Epilepsy Society (AES)
Summary:
Seizures that occur in the first few weeks of life are a major predictor of future adverse neurological outcomes. Currently approved antiepileptic drugs (AEDs) are effective in stopping seizures in less than 50% of these neonatal cases. The approved therapies can also have undesirable side effects.

Seizures that occur in the first few weeks of life are a major predictor of future adverse neurological outcomes. Currently approved antiepileptic drugs (AEDs) are effective in stopping seizures in less than 50% of these neonatal cases. The approved therapies can also have undesirable side effects.

In retrospective research reported December 7 at the 64th American Epilepsy Society annual meeting, all newborns in a study who received IV levetiracetam for their seizures had achieved acute seizure freedom within 72 hours of being treated. Improvement both in brain wave activity and in clinically observable behavior was seen in 86 percent of newborns in the study within an hour after the initial dosing.

Researchers at Scott & White Hospital / Texas A & M Health Science Center in Temple, TX, reviewed the charts of all term neonates (n=22) treated between January 2007 and December 2009. No seizures were recorded while on levetiracetam in 32 percent of the neonates after the initial dosing. Acute seizure freedom was seen in 64 percent within 24 hours, rising to 86 percent at 48 hours, and 100 percent at 72 hours. (Abstract 2.163)

All of the newborns were switched to oral levetiracetam and, of those, 81 percent were discharged home on levetiracetam monotherapy. No major immediate adverse side effects were reported during the follow up of two to six months.

Results of this study are based on a small sample and need to be confirmed by additional research. If confirmed, however, thousands of babies each year might be saved from a future with epilepsy and/or other neurological deficits.


Story Source:

The above story is based on materials provided by American Epilepsy Society (AES). Note: Materials may be edited for content and length.


Cite This Page:

American Epilepsy Society (AES). "IV drug could be major advance in halting acute seizures in newborns." ScienceDaily. ScienceDaily, 7 December 2010. <www.sciencedaily.com/releases/2010/12/101207155355.htm>.
American Epilepsy Society (AES). (2010, December 7). IV drug could be major advance in halting acute seizures in newborns. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2010/12/101207155355.htm
American Epilepsy Society (AES). "IV drug could be major advance in halting acute seizures in newborns." ScienceDaily. www.sciencedaily.com/releases/2010/12/101207155355.htm (accessed April 19, 2014).

Share This



More Health & Medicine News

Saturday, April 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins