Featured Research

from universities, journals, and other organizations

Attempting to predict epileptic seizure

Date:
December 14, 2010
Source:
American Institute of Physics
Summary:
While the causes of epileptic seizures continue to confound brain researchers, scientists have been exploring how changes in the coordinated activity of brain networks, monitored through electrodes, might help predict impending seizures.

While the causes of epileptic seizures continue to confound brain researchers, scientists have been exploring how changes in the coordinated activity of brain networks, as monitored through electrodes, might help predict impending seizures. A report in the American Institute of Physics' journal Chaos offers new insight into this possibility.

Two properties are commonly used to measure fluctuations in the activity of a brain network; one, known as L, relates to the overall connectedness between the activities of brain regions (or nodes), and the other, C, represents the probability that any two nodes are both interacting with a third node. Tracking changes in these variables, neuroscientists suspect, might offer a way to spot seizures in advance.

Most studies of complex brain networks have used only short-duration recordings of brain function, no more than a few minutes long. And, says physicist Marie-Therese Kuhnert -- a graduate student at the University of Bonn and first author of the CHAOS paper -- to really find seizure-predicting patterns, you need longer-term data.

Kuhnert and her colleagues, professors Christian Elger and Klaus Lehnertz, studied the brain recordings of 13 epilepsy patients undergoing pre-surgical evaluations. The data -- representing, in all cases, days of continuous recordings and seizure activity -- did indeed show fluctuations in L and C, but the two measures were "strongly influenced by the daily rhythms of the patient, sleep-wake cycles, and alterations of anticonvulsive medication," Kuhnert says. Upcoming seizures and even seizures themselves had little effect.

Surprisingly, Kuhnert and her colleagues found much more regularization of brain network activity at night. Previously, such regularization has been seen in healthy individuals, but never in epilepsy patients. "It remains to be investigated whether the increased regularization at night is causally related to epilepsy, whether it requires some treatment, or whether it can be regarded as a seizure-preventing mechanism," she says.


Story Source:

The above story is based on materials provided by American Institute of Physics. Note: Materials may be edited for content and length.


Journal Reference:

  1. Marie-Therese Kuhnert, Christian E. Elger, Klaus Lehnertz. Long-term variability of global statistical properties of epileptic brain networks. Chaos: An Interdisciplinary Journal of Nonlinear Science, 2010; 20 (4): 043126 DOI: 10.1063/1.3504998

Cite This Page:

American Institute of Physics. "Attempting to predict epileptic seizure." ScienceDaily. ScienceDaily, 14 December 2010. <www.sciencedaily.com/releases/2010/12/101214100236.htm>.
American Institute of Physics. (2010, December 14). Attempting to predict epileptic seizure. ScienceDaily. Retrieved September 22, 2014 from www.sciencedaily.com/releases/2010/12/101214100236.htm
American Institute of Physics. "Attempting to predict epileptic seizure." ScienceDaily. www.sciencedaily.com/releases/2010/12/101214100236.htm (accessed September 22, 2014).

Share This



More Health & Medicine News

Monday, September 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Liberia Pleads for Help to Fight Ebola

Liberia Pleads for Help to Fight Ebola

AP (Sep. 22, 2014) Liberia's finance minister is urging the international community to quickly follow through on pledges of cash to battle Ebola. Bodies are piling up in the capital Monrovia as the nation awaits more help. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Ebola Doctor Says Border Controls Critical

Ebola Doctor Says Border Controls Critical

AP (Sep. 22, 2014) A Florida doctor who helped fight the expanding Ebola outbreak in West Africa says the disease can be stopped, but only if nations quickly step up their response and make border control a priority. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Global Ebola Aid Increasing But Critics Say It's Late

Global Ebola Aid Increasing But Critics Say It's Late

Newsy (Sep. 21, 2014) More than 100 tons of medical supplies were sent to West Africa on Saturday, but aid workers say the global response is still sluggish. Video provided by Newsy
Powered by NewsLook.com
Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins