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Is different approach needed for acute diverticulitis in younger patients?

Date:
January 25, 2011
Source:
World Journal of Gastroenterology
Summary:
A research team from Portugal compared the natural history and course of acute diverticulitis in a younger age group with an older population to evaluate whether younger patients should be managed differently. They recommended that diverticulitis management should be based on the severity of the disease and not on the age of the patient.

Acute diverticulitis is the most common complication of diverticular disease, and its clinical presentation varies from mild local inflammation to full-blown perforation. After resolution of an acute episode, the best management strategy is as yet undefined, due to the risk of further episodes and the risk associated with elective surgical resection. Historically, surgical resection has been advocated after one episode of complicated diverticulitis (diverticulitis with perforation of the bowel wall, which manifests as intra-abdominal abscesses or peritonitis) and after one episode of uncomplicated disease (local inflammation) for patients younger than 50 years old. However, this aggressive strategy for younger patients has been questioned by several researchers.

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A research article to be published on January 14, 2011 in the World Journal of Gastroenterology addresses this question. The authors did a retrospective study to compare the natural history and the course of acute diverticulitis in a younger age group with that of an older population.

In this study, the patients younger than 50 years at first presentation of diverticulitis had less severe disease but a higher recurrence rate (25.8% vs 11.1%). All the patients with recurrent disease were managed with conservative treatment and for the majority of patients, the most severe attack of diverticulitis was the first. On multivariate analysis, age was the only factor predictive of recurrence.

The results show that acute diverticulitis is a mild disease with a low complication rate. In younger patients, there is a male predominance and the disease tends to be less severe than in the older age group, in spite of the higher recurrence rate. The clinical course of uncomplicated acute diverticulitis is similar both in younger and older patients. Therefore the same guidelines should be used in the treatment of both groups of patients.


Story Source:

The above story is based on materials provided by World Journal of Gastroenterology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Faria GR, Almeida AB, Moreira H, Pinto-de-Sousa J, Correiada-Silva P, Pimenta AP. Acute diverticulitis in younger patients: Any rationale for a different approach? World Journal of Gastroenterology, 2011; 17 (2): 207 DOI: 10.3748/wjg.v17.i2.207

Cite This Page:

World Journal of Gastroenterology. "Is different approach needed for acute diverticulitis in younger patients?." ScienceDaily. ScienceDaily, 25 January 2011. <www.sciencedaily.com/releases/2011/01/110125103918.htm>.
World Journal of Gastroenterology. (2011, January 25). Is different approach needed for acute diverticulitis in younger patients?. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2011/01/110125103918.htm
World Journal of Gastroenterology. "Is different approach needed for acute diverticulitis in younger patients?." ScienceDaily. www.sciencedaily.com/releases/2011/01/110125103918.htm (accessed October 25, 2014).

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