Featured Research

from universities, journals, and other organizations

Experts propose global guidelines for safe use of Kava

Date:
February 28, 2011
Source:
University of Melbourne
Summary:
Medical and scientific experts propose a global framework for the safe production and use of the medicinal plant Kava, including further clinical testing In Australia.

The South-Pacific plant has been traditionally used to reduce stress and anxiety but is restricted in some countries.

Leading world Kava experts Dr Jerome Sarris from the University of Melbourne, Australia; Professor Rolf Teschke from Wolfgang Goethe-University, Frankfurt, Germany; and Dr Vincent Lebot from CIRAD, Port-Vila, Vanuatu, have proposed a six-point plan that is intended to become the framework to assist in the re-introduction of Kava to restricted countries. The framework will ensure only high quality Kava to be consumed throughout the Pacific and the rest of the world.

The framework was recently published in the international journals Phytomedicine and The British Journal of Clinical Pharmacology.

"Kava can potentially be used safely if this framework for production and use is adopted," Dr Jerome Sarris said.

Kava was restricted for use in 2002 in Europe, United Kingdom and Canada over concerns it may cause liver problems (on average one case per every 50 million doses). This was considered to be potentially due, in part, to companies using chemical extracts from poor quality material using an incorrect type of Kava.

Dr Sarris said the future regulatory and commercial strategies should focus not only on the standardisation of medicinal Kava products and traditional Kava extracts, but also on thorough surveillance during the manufacturing process to improve Kava quality for safe human use.

"It is intended now that these recommendations be taken up by Kava producing Pacific Island countries in order to reinvigorate the Kava industry and provide a pathway back to safe global use of the plant," Dr Sarris said.

The use of the plant as a treatment for generalised anxiety is part of two human trials currently being conducted by Dr Sarris in Melbourne Australia, where it is available over the counter.

In Australia in 2005, the Australian Therapeutics Goods Administration allowed for water soluble extracts of Kava to be used for medicinal purposes.

He said preliminary results with the Mediherb extract showed the kava extract used was safe and effective in reducing anxiety.

"We do however, need a larger study to validate this result," Dr Sarris said.

The six-point framework for the safe production of Kava is as follows:

1) Use of Kava plants at least five years old ("noble" type of Kava cultivar is preferred, as it is traditionally considered safe)

2) Use of the peeled rhizome (root) of Kava plant (not leaves or aerial parts)

3) Water-soluble extract for Kava (not alcohol or chemical solution to extract constituents)

4) Dosage recommendations of less than 250 mg of kavalactones (the active chemicals) per day for medicinal use

5) Systematic rigorous future research investigating safety issues (potentially from poorly stored and manufactured Kava material, and/or incorrect cultivar and plant material), and human clinical trials using noble cultivars prepared via good pharmaceutical manufacturing practice

6) A Pan-Pacific quality control system enforced by strict policing.


Story Source:

The above story is based on materials provided by University of Melbourne. Note: Materials may be edited for content and length.


Cite This Page:

University of Melbourne. "Experts propose global guidelines for safe use of Kava." ScienceDaily. ScienceDaily, 28 February 2011. <www.sciencedaily.com/releases/2011/02/110228104446.htm>.
University of Melbourne. (2011, February 28). Experts propose global guidelines for safe use of Kava. ScienceDaily. Retrieved September 1, 2014 from www.sciencedaily.com/releases/2011/02/110228104446.htm
University of Melbourne. "Experts propose global guidelines for safe use of Kava." ScienceDaily. www.sciencedaily.com/releases/2011/02/110228104446.htm (accessed September 1, 2014).

Share This




More Plants & Animals News

Monday, September 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

We've Got Mites Living In Our Faces And So Do You

We've Got Mites Living In Our Faces And So Do You

Newsy (Aug. 30, 2014) A new study suggests 100 percent of adult humans (those over 18 years of age) have Demodex mites living in their faces. Video provided by Newsy
Powered by NewsLook.com
Washington Wildlife Center Goes Nuts Over Baby Squirrels

Washington Wildlife Center Goes Nuts Over Baby Squirrels

Reuters - US Online Video (Aug. 30, 2014) An animal rescue in Washington state receives an influx of orphaned squirrels, keeping workers busy as they nurse them back to health. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Experimental Ebola Drug ZMapp Cures Lab Monkeys Of Disease

Experimental Ebola Drug ZMapp Cures Lab Monkeys Of Disease

Newsy (Aug. 29, 2014) In a new study, a promising experimental treatment for Ebola managed to cure a group of infected macaque monkeys. Video provided by Newsy
Powered by NewsLook.com
Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins