Featured Research

from universities, journals, and other organizations

AIDS associated with an increased risk of some stomach, esophageal cancers

Date:
April 4, 2011
Source:
American Association for Cancer Research
Summary:
AIDS patients have nearly a seven-fold increased risk of malignancies of the stomach compared to the general population, according to new study results. Their risk of malignancies of the esophagus is almost three times higher than in the general population. In both organs, these results are mainly due to a dramatically increased risk of lymphomas, but risks are also increased for carcinomas.

Among people with AIDS, the risk of stomach and esophageal malignancies is higher than among the general population, according to study results presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.

"People diagnosed with AIDS are living longer due to improved therapies. However, they are at increased risk of developing a number of different cancers, including Kaposi's sarcoma and several lymphomas. The risk of stomach and esophageal cancers in AIDS patients has not previously been fully evaluated," said E. Christina Persson, Ph.D., a postdoctoral fellow at the National Cancer Institute.

Persson and colleagues utilized data from the HIV/AIDS Cancer Match Study, a linkage of 15 U.S. population-based HIV/AIDS and cancer registries with data from 1980 through 2007. The study included 600,000 men and women diagnosed with AIDS, of whom 1,166 developed stomach malignancies and 240 developed esophageal malignancies.

Overall, people with AIDS had a 6.9-fold increased incidence of stomach malignancies compared to the general population. The risk was increased 70 percent for stomach carcinomas, with similar increases for proximal (cardia) and distal (non-cardia) carcinomas. The risk for stomach lymphomas was 36-fold higher.

The overall risk of esophageal malignancies was 2.7 times higher among people with AIDS than in the general population. Risk was increased 54 percent for squamous cell carcinomas, 101 percent for adenocarcinomas, and 261-fold for lymphomas of the esophagus.

Persson said that the increased lymphoma risk among patients with AIDS was expected, but the increased risk for carcinomas is a new finding. Additionally, the size of this study allowed the researchers to look at carcinoma subtypes.

"This study is unique because of its large size, which allowed us to look more closely at the different histologic and anatomic subsites of the tumors," said Persson. "It will be important for us to evaluate trends in risk over time, particularly in the modern HIV treatment era."


Story Source:

The above story is based on materials provided by American Association for Cancer Research. Note: Materials may be edited for content and length.


Cite This Page:

American Association for Cancer Research. "AIDS associated with an increased risk of some stomach, esophageal cancers." ScienceDaily. ScienceDaily, 4 April 2011. <www.sciencedaily.com/releases/2011/04/110404111042.htm>.
American Association for Cancer Research. (2011, April 4). AIDS associated with an increased risk of some stomach, esophageal cancers. ScienceDaily. Retrieved August 30, 2014 from www.sciencedaily.com/releases/2011/04/110404111042.htm
American Association for Cancer Research. "AIDS associated with an increased risk of some stomach, esophageal cancers." ScienceDaily. www.sciencedaily.com/releases/2011/04/110404111042.htm (accessed August 30, 2014).

Share This




More Health & Medicine News

Saturday, August 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

3 Things To Know About The Ebola Outbreak's Progression

3 Things To Know About The Ebola Outbreak's Progression

Newsy (Aug. 29, 2014) Here are three things you need to know about the deadly Ebola outbreak's progression this week. Video provided by Newsy
Powered by NewsLook.com
Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com
Who Could Be Burnt by WHO's E-Cigs Move?

Who Could Be Burnt by WHO's E-Cigs Move?

Reuters - Business Video Online (Aug. 28, 2014) The World Health Organisation has called for the regulation of electronic cigarettes as both tobacco and medical products. Ciara Lee looks at the impact of the move on the tobacco industry. Video provided by Reuters
Powered by NewsLook.com
CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

Newsy (Aug. 28, 2014) CDC director Tom Frieden says the Ebola outbreak is even worse than he feared. But he also said there's still hope to contain it. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins