Featured Research

from universities, journals, and other organizations

New drug may reduce seizures in epilepsy

Date:
April 14, 2011
Source:
American Academy of Neurology
Summary:
A new drug called perampanel appears to significantly reduce seizures in people with hard-to-control epilepsy, according to results of the first clinical trial to test the higher 12 mg dose of the drug.

A new drug called perampanel appears to significantly reduce seizures in people with hard-to-control epilepsy, according to results of the first clinical trial to test the higher 12 mg dose of the drug. The late-breaking research will be presented at the 63rd Annual Meeting of the American Academy of Neurology, April 9-16, 2011, in Honolulu.

"For about one-third of people with epilepsy, the drugs either don't stop their seizures or the side effects are not tolerable," said study author Jacqueline French, MD, with New York University in New York. French is also a Fellow of the American Academy of Neurology. "If this drug is approved by the Food and Drug Administration (FDA), it will be another tool in our arsenal for combating or reducing seizures in people with difficult to treat epilepsy."

The study involved 387 people in the United States and Latin America who had uncontrolled epilepsy and were currently taking one to three other anti-seizure drugs. Participants were assigned to receive either eight or 12 milligrams of perampanel or a placebo pill once daily for 19 weeks in addition to their regular treatment.

Patients who took the 12 milligram dose of perampanel had a 14-percent reduction in seizures in a 28-day period compared to those who took the placebo. Those who took the eight milligram dose cut their seizure frequency by nearly six percent compared to those who took the placebo.

The most common side effects of the drug were dizziness, drowsiness, irritability, headache, falls and ataxia, which is a lack of muscle coordination.

"These findings provide further evidence of the effectiveness and safety of perampanel as an added treatment option to reduce seizures," said French. "Plans are to submit the drug for FDA approval this year."

The study was supported by Eisai Inc.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Neurology. "New drug may reduce seizures in epilepsy." ScienceDaily. ScienceDaily, 14 April 2011. <www.sciencedaily.com/releases/2011/04/110413161244.htm>.
American Academy of Neurology. (2011, April 14). New drug may reduce seizures in epilepsy. ScienceDaily. Retrieved October 23, 2014 from www.sciencedaily.com/releases/2011/04/110413161244.htm
American Academy of Neurology. "New drug may reduce seizures in epilepsy." ScienceDaily. www.sciencedaily.com/releases/2011/04/110413161244.htm (accessed October 23, 2014).

Share This



More Health & Medicine News

Thursday, October 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Working Mother (Oct. 22, 2014) Is your child ready? Video provided by Working Mother
Powered by NewsLook.com
U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

Newsy (Oct. 22, 2014) Now that the U.S. is restricting travel from West Africa, some are dropping questions about a travel ban and instead asking about visa bans. Video provided by Newsy
Powered by NewsLook.com
US to Track Everyone Coming from Ebola Nations

US to Track Everyone Coming from Ebola Nations

AP (Oct. 22, 2014) Stepping up their vigilance against Ebola, federal authorities said Wednesday that everyone traveling into the US from Ebola-stricken nations will be monitored for symptoms for 21 days. (Oct. 22) Video provided by AP
Powered by NewsLook.com
Doctors Help Paralysed Man Walk Again, Patient in Disbelief

Doctors Help Paralysed Man Walk Again, Patient in Disbelief

AFP (Oct. 22, 2014) Polish doctors describe how they helped a paralysed man walk again, with the patient in disbelief at the return of sensation to his legs. Duration: 1:04 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins