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Evidence-based guideline for thoracic radiotherapy

Date:
April 27, 2011
Source:
American Society for Radiation Oncology
Summary:
The American Society for Radiation Oncology has developed a guideline for the use of external beam radiation therapy, endobronchial brachytherapy and concurrent chemotherapy to palliate thoracic symptoms caused by advanced lung cancer.

The American Society for Radiation Oncology (ASTRO) has developed a guideline for the use of external beam radiation therapy, endobronchial brachytherapy and concurrent chemotherapy to palliate thoracic symptoms caused by advanced lung cancer. The guideline will be published in Practical Radiation Oncology, an official journal of ASTRO.

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Many patients whose lung cancer has spread receive radiation therapy to treat symptoms related to cancer, such as cough, shortness of breath, bronchial obstruction and chest pain. However, the exact treatment approach can vary from doctor to doctor. This variation caused the Guidelines Subcommittee of ASTRO's Clinical Affairs and Quality Committee (CAQC) to identify the use of palliative thoracic (or chest) radiation therapy as a high-priority topic needing an evidence-based guideline.

This panel was co-chaired by George Rodrigues, MD, MSc, a radiation oncologist and clinician scientist at London Health Sciences Centre in London, Ontario, Canada, and Benjamin Movsas, MD, chairman of radiation oncology at Henry Ford Health System in Detroit.

"Radiation therapy can be extremely helpful to alleviate symptoms caused by lung cancer, such as shortness of breath and chest pain," Dr. Rodrigues said.

ASTRO's Board of Directors then put together a multidisciplinary task force that was charged with reviewing and synthesizing the current evidence to develop a guideline to help radiation oncologists determine the appropriate use of external beam radiation therapy, endobronchial brachytherapy and concurrent chemotherapy for palliative intent for lung cancer patients.

The task force's main findings are:

1. Various regimens of thoracic external beam radiation therapy are very effective for palliation of symptoms, with moderately higher dose regimens associated with a modest improvement in survival for selected patients primarily with good performance status.

2. There is no evidence to recommend the use of endobronchial brachytherapy in the routine initial palliative management of lung cancer. Endobronchial brachytherapy is a type of internal radiation therapy used to treat lung cancer in or near the patient's airway.

3. There is no added benefit to patients to use chemotherapy at the same time as radiation therapy in the relief of thoracic symptoms for lung cancer patients. However, optimally integrating sequential chemotherapy and radiation therapy is important in the management of lung cancer symptoms.


Story Source:

The above story is based on materials provided by American Society for Radiation Oncology. Note: Materials may be edited for content and length.


Journal Reference:

  1. George Rodrigues, Gregory M.M. Videtic, Ranjan Sur, Andrea Bezjak, Jeffrey Bradley, Carol A. Hahn, Corey Langer, Keith L. Miller, Benjamin J. Moeller, Kenneth Rosenzweig, Benjamin Movsas. Palliative thoracic radiotherapy in lung cancer: An American Society for Radiation Oncology evidence-based clinical practice guideline. Practical Radiation Oncology, 2011; 1 (2): 60 DOI: 10.1016/j.prro.2011.01.005

Cite This Page:

American Society for Radiation Oncology. "Evidence-based guideline for thoracic radiotherapy." ScienceDaily. ScienceDaily, 27 April 2011. <www.sciencedaily.com/releases/2011/04/110427132027.htm>.
American Society for Radiation Oncology. (2011, April 27). Evidence-based guideline for thoracic radiotherapy. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2011/04/110427132027.htm
American Society for Radiation Oncology. "Evidence-based guideline for thoracic radiotherapy." ScienceDaily. www.sciencedaily.com/releases/2011/04/110427132027.htm (accessed November 26, 2014).

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