Featured Research

from universities, journals, and other organizations

Green light for flu vaccine in transplant recipients, study suggests

Date:
April 28, 2011
Source:
American Society of Nephrology
Summary:
Getting vaccinated against the flu lowers kidney transplant recipients' risk of organ loss and death, according to a new study. The results suggest that concerns about the safety of the influenza vaccine in transplant recipients are unwarranted.

Getting vaccinated against the flu lowers kidney transplant recipients' risk of organ loss and death, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The results suggest that concerns about the safety of the influenza vaccine in transplant recipients are unwarranted.

Influenza can cause severe illness and even death in some individuals. Organ transplant recipients and those taking immunosuppressant medications face a particularly high risk of dying after being infected. Protection against the flu is especially important for these patients, but earlier reports have suggested that influenza vaccination might activate an immune response that could trigger rejection of transplanted organs. Some studies have also suggested that the immunosuppressant medications that transplant recipients take may decrease the effectiveness of the influenza vaccine.

To investigate these issues, Frank Hurst, MD (Walter Reed Army Medical Center and F. Edward Hebert School of Medicine) and his colleagues assessed Medicare claims for influenza vaccination and influenza infections in 51,730 adult Medicare patients first transplanted from January 2000 to July 2006 and were followed through October 2006. There were 9,678 (18.7%) patients who were vaccinated against the flu in the first year after transplantation. These individuals were 23% less likely to experience organ loss and 18% less likely to die during the study period than individuals who were not vaccinated. A total of 310 (0.6%) patients got the flu. They were no more likely to experience organ loss than patients who did not get the flu.

These findings do not support withholding immunization on the basis of concerns that the influenza vaccine could negatively affect transplanted organs. The authors noted, however, that no data are currently available to prove that influenza vaccination actually prevents the flu in transplant recipients.


Story Source:

The above story is based on materials provided by American Society of Nephrology. Note: Materials may be edited for content and length.


Journal Reference:

  1. F. P. Hurst, J. J. Lee, R. M. Jindal, L. Y. Agodoa, K. C. Abbott. Outcomes Associated with Influenza Vaccination in the First Year after Kidney Transplantation. Clinical Journal of the American Society of Nephrology, 2011; DOI: 10.2215/CJN.05430610

Cite This Page:

American Society of Nephrology. "Green light for flu vaccine in transplant recipients, study suggests." ScienceDaily. ScienceDaily, 28 April 2011. <www.sciencedaily.com/releases/2011/04/110428201108.htm>.
American Society of Nephrology. (2011, April 28). Green light for flu vaccine in transplant recipients, study suggests. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2011/04/110428201108.htm
American Society of Nephrology. "Green light for flu vaccine in transplant recipients, study suggests." ScienceDaily. www.sciencedaily.com/releases/2011/04/110428201108.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Microneedle Patch Promises Painless Pricks

Microneedle Patch Promises Painless Pricks

Reuters - Innovations Video Online (Oct. 18, 2014) Researchers at The National University of Singapore have invented a new microneedle patch that could offer a faster and less painful delivery of drugs such as insulin and painkillers. Video provided by Reuters
Powered by NewsLook.com
Raw: Nurse Nina Pham Arrives in Maryland

Raw: Nurse Nina Pham Arrives in Maryland

AP (Oct. 17, 2014) The first nurse to be diagnosed with Ebola at a Dallas hospital walked down the stairs of an executive jet into an ambulance at an airport in Frederick, Maryland, on Thursday. Pham will be treated at the National Institutes of Health. (Oct. 16) Video provided by AP
Powered by NewsLook.com
Raw: Cruise Ship Returns to US Over Ebola Fears

Raw: Cruise Ship Returns to US Over Ebola Fears

AP (Oct. 17, 2014) A Caribbean cruise ship carrying a Dallas health care worker who is being monitored for signs of the Ebola virus is heading back to Texas, US, after being refused permission to dock in Cozumel, Mexico. (Oct. 17) Video provided by AP
Powered by NewsLook.com
Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

AFP (Oct. 17, 2014) All four suspected Ebola cases admitted to hospitals in Spain on Thursday have tested negative for the deadly virus in a first round of tests, the government said Friday. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins