Featured Research

from universities, journals, and other organizations

Stem cell technology used in unique surgery

Date:
May 9, 2011
Source:
University of Gothenburg
Summary:
For the first time, researchers in Sweden have produced a blood vessel from stem cells and then used it in an operation on a 10-year-old girl. Surgeons were able to create a new connection with the aid of this blood vessel between the liver and the intestines, necessary to cure the girl. The girl is now in good health, and her prognosis is very good.

For the first time, researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have produced a blood vessel from stem cells and then used it in an operation on a 10-year-old girl at the Sahlgrenska University Hospital. Surgeon and Professor Michael Olausson was able to create a new connection with the aid of this blood vessel between the liver and the intestines, necessary to cure the girl. The girl is now in good health, and her prognosis is very good.

Related Articles


The girl developed during her first year of life a blood clot in the blood vessel that leads blood from the intestines to the liver. This introduced the risk that she would experience life-threatening internal bleeding. The condition can be cured if it is possible to direct the blood along the correct path, back into the liver. In optimal cases, the surgery can be performed using blood vessels from other parts of the patient's body, but a liver transplant may be necessary if the surgery is unsuccessful due to a lack of sufficient blood vessels. A liver transplant will involve subsequent lifelong treatment with immunosuppressive drugs.

Blood vessels from a dead donor were used in the present case. The vessel was then chemically treated to remove all cells RNA and DNA. This left just the supporting tissue. Stem cells were then obtained from the girl's bone marrow and these were added to the supporting tissue. A new blood vessel grew in just under four weeks. This was used during the surgery in order to create the new connection between the liver and the intestines, necessary to cure the girl.

"We carried out the surgery over three months ago now, and the result was very good, with no serious complications. To our knowledge this is the first procedure of this type in the world, says Michael Olausson. The girl is in good health, and we believe that her prognosis is very good. Since the vessel was created with the girl's own stem cells, she does not need to take drugs to prevent rejection," says Michael Olausson at the Transplant Centre, Sahlgrenska University Hospital and professor at the Sahlgrenska Academy.

The procedure shows that it is possible to create new blood vessels from stem cells, using a previous blood vessel as a template. This can lead to the condition that the girl suffered from being treated more easily, and with less risk for the patient. The result of this operation may have implications not only for the condition the girl was suffering from, but also in a number of other fields of research.

"The next step is to intensify research into the recreation of other organs, and to develop methods that can be used for arteries. This can help, among others, patients who need dialysis and those needing surgery for the coronary arteries. It may also help those needing complete organs," says Michael Olausson, who adds:

"There may also be major financial benefits for the healthcare system, particularly if it proves possible to produce, for example, complete kidneys by this method, since the consumption of drugs will be dramatically reduced. For the patients, it means that the undesired effects of the drugs that must currently be used will be avoided."


Story Source:

The above story is based on materials provided by University of Gothenburg. Note: Materials may be edited for content and length.


Cite This Page:

University of Gothenburg. "Stem cell technology used in unique surgery." ScienceDaily. ScienceDaily, 9 May 2011. <www.sciencedaily.com/releases/2011/05/110509113302.htm>.
University of Gothenburg. (2011, May 9). Stem cell technology used in unique surgery. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2011/05/110509113302.htm
University of Gothenburg. "Stem cell technology used in unique surgery." ScienceDaily. www.sciencedaily.com/releases/2011/05/110509113302.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com
Winter Can Cause Depression — Here's How To Combat It

Winter Can Cause Depression — Here's How To Combat It

Newsy (Nov. 23, 2014) Millions of American suffer from seasonal depression every year. It can lead to adverse health effects, but there are ways to ease symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins