Featured Research

from universities, journals, and other organizations

BPA lowers male fertility, mouse study finds

Date:
June 6, 2011
Source:
The Endocrine Society
Summary:
Daily exposure to a chemical that is prevalent in the human environment, bisphenol A, causes lowered fertility in male mice, according to the results of a new study.

Daily exposure to a chemical that is prevalent in the human environment, bisphenol A (BPA), causes lowered fertility in male mice, according to the results of a new study that being presented at The Endocrine Society's 93rd Annual Meeting in Boston.

Related Articles


Mice that received daily BPA injections for two months had lower sperm counts and testosterone levels than those of mice that received saline injections without BPA, investigators from Banaras Hindu University in Varanasi, India, found. Compared with untreated controls, mice exposed to BPA produced litters that were 50 percent smaller.

"We are being exposed to BPA in our daily lives at a level much higher than the safe recommended exposure," said the study's principal author, Surya Singh, PhD, associate professor in the university's biochemistry department. "In this study, we are trying to explore what the outcome can be if we are continuously exposed to BPA in our routine life."

BPA-exposed mice received a dose that was twice the daily upper limit of safe exposure recommended by the U.S. Food and Drug Administration and the Environmental Protection Agency.

At a BPA dosage of 100 micrograms per kilogram of body weight daily, the mice also had structural defects in their testicles and were considered subfertile. If the same dose had been given longer than two months, Singh speculated that it might lead to infertility.

However, he said they saw lowered fertility in the mice as early as one month of BPA exposure.

"Even short-term exposure to BPA could be dangerous to fertility, but we are still investigating this possibility," Singh said.

These new research findings add to a growing body of scientific evidence that links exposure to BPA, an endocrine (hormone) disrupter, with numerous adverse health effects, including on reproductive function.

Human exposure to BPA comes from sources such as epoxy resin-lined food cans and hard polycarbonate plastics, which leach the chemical, especially when heated to high temperatures.


Story Source:

The above story is based on materials provided by The Endocrine Society. Note: Materials may be edited for content and length.


Cite This Page:

The Endocrine Society. "BPA lowers male fertility, mouse study finds." ScienceDaily. ScienceDaily, 6 June 2011. <www.sciencedaily.com/releases/2011/06/110606092740.htm>.
The Endocrine Society. (2011, June 6). BPA lowers male fertility, mouse study finds. ScienceDaily. Retrieved March 3, 2015 from www.sciencedaily.com/releases/2011/06/110606092740.htm
The Endocrine Society. "BPA lowers male fertility, mouse study finds." ScienceDaily. www.sciencedaily.com/releases/2011/06/110606092740.htm (accessed March 3, 2015).

Share This


More From ScienceDaily



More Plants & Animals News

Tuesday, March 3, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Rare Goblin Shark Found in Australia

Rare Goblin Shark Found in Australia

AFP (Mar. 3, 2015) A goblin shark, a rare sea creature described as an &apos;alien of the deep&apos; is found off Australia and delivered to the Australian Museum in Sydney. Duration: 01:25 Video provided by AFP
Powered by NewsLook.com
500 Snakes Surprise Construction Workers In Canada

500 Snakes Surprise Construction Workers In Canada

Newsy (Mar. 2, 2015) Hundreds of snakes, disturbed by a construction project, were relocated to a wildlife rescue association in Canada. Video provided by Newsy
Powered by NewsLook.com
Going Gluten-Free Could Get You A Tax Break

Going Gluten-Free Could Get You A Tax Break

Newsy (Mar. 2, 2015) If a doctor advises you to remove gluten from your diet, you could get a tax deduction on the amount you spend on gluten-free foods. Video provided by Newsy
Powered by NewsLook.com
Zookeepers Copy Animal Poses In Hilarious Viral Photos

Zookeepers Copy Animal Poses In Hilarious Viral Photos

Buzz60 (Mar. 2, 2015) Zookeepers at the Symbio Wildlife Park in Helensburgh, Australia decided to take some of their favorite animal photos and recreate them by posing just like the animals. Jen Markham (@jenmarkham) has the story. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins